Please use this identifier to cite or link to this item:
https://olympias.lib.uoi.gr/jspui/handle/123456789/21400Full metadata record
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Kyriakopoulou, Z. | en |
| dc.contributor.author | Pliaka, V. | en |
| dc.contributor.author | Tsakogiannis, D. | en |
| dc.contributor.author | Ruether, I. G. | en |
| dc.contributor.author | Komiotis, D. | en |
| dc.contributor.author | Gartzonika, C. | en |
| dc.contributor.author | Levidiotou-Stefanou, S. | en |
| dc.contributor.author | Markoulatos, P. | en |
| dc.date.accessioned | 2015-11-24T19:14:50Z | - |
| dc.date.available | 2015-11-24T19:14:50Z | - |
| dc.identifier.issn | 1572-994X | - |
| dc.identifier.uri | https://olympias.lib.uoi.gr/jspui/handle/123456789/21400 | - |
| dc.rights | Default Licence | - |
| dc.title | Genome analysis of two type 6 echovirus (E6) strains recovered from sewage specimens in Greece in 2006 | en |
| heal.type | journalArticle | - |
| heal.type.en | Journal article | en |
| heal.type.el | Άρθρο Περιοδικού | el |
| heal.identifier.primary | 10.1007/s11262-011-0688-3 | - |
| heal.identifier.secondary | http://www.ncbi.nlm.nih.gov/pubmed/22090198 | - |
| heal.identifier.secondary | http://www.springerlink.com/content/8u050787110435j2/fulltext.pdf | - |
| heal.language | en | - |
| heal.access | campus | - |
| heal.recordProvider | Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής | el |
| heal.publicationDate | 2012 | - |
| heal.abstract | Echovirus 6 (E6) is one of the main enteroviral serotypes that was isolated from cases of aseptic meningitis and encephalitis during the last years in Greece. Two E6 (LR51A5 and LR61G3) were isolated from the sewage treatment plant unit in Larissa, Greece, in May 2006, 1 year before their characterization from aseptic meningitis cases. The two isolates were initially found to be intra-serotypic recombinants in the genomic region VP1, a finding that initiated a full genome sequence analysis. In the present study, nucleotide, amino acid, and phylogenetic analyses for all genomic regions were conducted. For the detection of recombination events, Simplot and bootscan analyses were carried out. The continuous phylogenetic relationship in 2C-3D genomic region of strains LR51A5 and LR61G3 with E30 isolated in France in 2002-2005 indicated that the two strains were recombinants. SimPlot and Bootscan analyses confirmed that LR51A5 and LR61G3 carry an inter-serotypic recombination in the 2C genomic region. The present study provide evidence that recombination events occurred in the regions VP1 (intraserotypic) and non-capsid (interserotypic) during the evolution of LR51A5 and LR61G3, supporting the statement that the genomes of circulating enteroviruses are a mosaic of genomic regions of viral strains of the same or different serotypes. In conclusion, full genome sequence analysis of circulating enteroviral strains is a prerequisite to understand the complexity of enterovirus evolution. | en |
| heal.journalName | Virus Genes | en |
| heal.journalType | peer-reviewed | - |
| heal.fullTextAvailability | TRUE | - |
| Appears in Collections: | Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά) - ΙΑΤ | |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| Kyriakopoulou-2012-Genome analysis of t.pdf | 518.87 kB | Adobe PDF | View/Open Request a copy |
This item is licensed under a Creative Commons License
