Please use this identifier to cite or link to this item: https://olympias.lib.uoi.gr/jspui/handle/123456789/21353
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dc.contributor.authorKalamidas, S. A.en
dc.contributor.authorKotoulas, O. B.en
dc.date.accessioned2015-11-24T19:14:37Z-
dc.date.available2015-11-24T19:14:37Z-
dc.identifier.issn0213-3911-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/21353-
dc.rightsDefault Licence-
dc.subjectAnimalsen
dc.subjectAnimals, Newbornen
dc.subjectCyclic AMP/metabolismen
dc.subjectGlucosidases/metabolismen
dc.subjectHepatocytes/enzymology/*metabolism/ultrastructureen
dc.subjectLiver Glycogen/*metabolismen
dc.subjectMicroscopy, Electronen
dc.subjectPhosphoric Monoester Hydrolases/metabolismen
dc.subjectRatsen
dc.subjectRats, Wistaren
dc.subjectTissue Fixationen
dc.titleGlycogen autophagy in newborn rat hepatocytesen
heal.typejournalArticle-
heal.type.enJournal articleen
heal.type.elΆρθρο Περιοδικούel
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/11005224-
heal.languageen-
heal.accesscampus-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.publicationDate2000-
heal.abstractGlycogen autophagy in newborn rat hepatocytes was studied by using enzyme determinations and electron microscopy. Cyclic AMP induced glycogen autophagy in these cells. Glycogen-hydrolyzing acid glucosidase activity increased whereas acid mannose 6-phosphatase activity decreased in the liver of these animals. Parenteral glucose, which prevents postnatal glucagon secretion and tissue cyclic AMP elevation, and propranolol which antagonizes cyclic AMP, inhibited glycogen autophagy. Glucosidase activity decreased and phosphatase activity increased. These findings raise the possibility that cyclic AMP-induced autophagic mechanisms in newborn rat hepatocytes are associated with changes in the activity of acid mannose 6-phosphatase.en
heal.journalNameHistol Histopatholen
heal.journalTypepeer-reviewed-
heal.fullTextAvailabilityTRUE-
Appears in Collections:Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά) - ΙΑΤ

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