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dc.contributor.authorSideris, D. A.en
dc.contributor.authorKontoyannis, D. A.en
dc.contributor.authorMoulopoulos, S. D.en
dc.date.accessioned2015-11-24T19:13:50Z-
dc.date.available2015-11-24T19:13:50Z-
dc.identifier.issn0167-5273-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/21231-
dc.rightsDefault Licence-
dc.subjectAgeden
dc.subjectAnti-Arrhythmia Agents/*therapeutic useen
dc.subjectAprindine/adverse effects/*therapeutic useen
dc.subjectCardiac Complexes, Premature/chemically induceden
dc.subjectElectrocardiographyen
dc.subjectHumansen
dc.subjectIndenes/*therapeutic useen
dc.subjectMaleen
dc.subjectTachycardia/*drug therapy/physiopathologyen
dc.titleTorsade des pointes and aprindineen
heal.typejournalArticle-
heal.type.enJournal articleen
heal.type.elΆρθρο Περιοδικούel
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/2580805-
heal.identifier.secondaryhttp://ac.els-cdn.com/0167527385900968/1-s2.0-0167527385900968-main.pdf?_tid=46a67d6ca3d906d15ae0c274ba1e89b7&acdnat=1337847527_45c009288189a657748c82953ff9dafd-
heal.languageen-
heal.accesscampus-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.publicationDate1985-
heal.abstractAprindine was given orally to an 88-year-old patient with atrial fibrillation and ventricular premature depolarizations. The premature beats disappeared and sinus rhythm was restored on the third day of treatment. While on aprindine the QT interval was prolonged and the U wave became very prominent. The aprindine was stopped but 36 hr following the last oral dose, ventricular arrhythmia appeared with the characters of torsade des pointes. Three such episodes occurred within 24 hr. It is suggested that aprindine both eliminated the premature depolarizations and rendered the myocardium vulnerable by prolonging the QT interval. On discontinuing the medicament the premature beats reappeared while the myocardium was still vulnerable, so that torsade des pointes resulted.en
heal.journalNameInt J Cardiolen
heal.journalTypepeer-reviewed-
heal.fullTextAvailabilityTRUE-
Appears in Collections:Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά) - ΙΑΤ

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