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  3. Σχολή Επιστημών Υγείας
  4. Τμήμα Ιατρικής
  5. Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά) - ΙΑΤ
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Please use this identifier to cite or link to this item: https://olympias.lib.uoi.gr/jspui/handle/123456789/21177
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dc.contributor.authorMoutsopoulos, H. M.en
dc.contributor.authorHooks, J. J.en
dc.contributor.authorChan, C. C.en
dc.contributor.authorDalavanga, Y. A.en
dc.contributor.authorSkopouli, F. N.en
dc.contributor.authorDetrick, B.en
dc.date.accessioned2015-11-24T19:13:19Z-
dc.date.available2015-11-24T19:13:19Z-
dc.identifier.issn0003-4967-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/21177-
dc.rightsDefault Licence-
dc.subjectAdulten
dc.subjectAgeden
dc.subjectFemaleen
dc.subjectHLA-DR Antigensen
dc.subjectHistocompatibility Antigens Class II/*analysisen
dc.subjectHumansen
dc.subjectImmunoenzyme Techniquesen
dc.subjectLymphocytes/immunologyen
dc.subjectMaleen
dc.subjectMiddle Ageden
dc.subjectSalivary Glands/*immunologyen
dc.subjectSalivary Glands, Minor/*immunology/pathologyen
dc.subjectSjogren's Syndrome/*immunology/pathologyen
dc.titleHLA-DR expression by labial minor salivary gland tissues in Sjogren's syndromeen
heal.typejournalArticle-
heal.type.enJournal articleen
heal.type.elΆρθρο Περιοδικούel
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/3527087-
heal.identifier.secondaryhttp://ard.bmj.com/content/45/8/677.full.pdf-
heal.languageen-
heal.accesscampus-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.publicationDate1986-
heal.abstractMinor salivary gland biopsy specimens from patients with Sjogren's syndrome (primary and secondary) and from normal controls were examined with the four step biotin-avidin-immunoperoxidase assay. The composition of the infiltrating cells was similar in patients with both primary and secondary Sjogren's syndrome, consisting primarily of T lymphocytes with predominance of T helper/inducer cells. B lymphocytes (Leu-14) were approximately 20-35% of the infiltrating lymphocytes, while only a few OKM1 (monocytes/macrophages) cells and Leu-7+ (natural killer; NK) cells were observed. The majority of infiltrating lymphocytes expressed HLA-DR antigens. In the biopsy specimens of the controls there were no infiltrates; the scattered lymphocytes, however, were also predominantly T lymphocytes. Finally, the glandular epithelial cells (ducts and acini) were inappropriately expressing HLA-DR antigens, in contrast with controls where minimal HLA-DR expression was found.en
heal.journalNameAnn Rheum Disen
heal.journalTypepeer-reviewed-
heal.fullTextAvailabilityTRUE-
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