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https://olympias.lib.uoi.gr/jspui/handle/123456789/21133Full metadata record
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Paraskevaidis, E. | en |
| dc.contributor.author | Koliopoulos, G. | en |
| dc.contributor.author | Alamanos, Y. | en |
| dc.contributor.author | Malamou-Mitsi, V. | en |
| dc.contributor.author | Lolis, E. D. | en |
| dc.contributor.author | Kitchener, H. C. | en |
| dc.date.accessioned | 2015-11-24T19:12:56Z | - |
| dc.date.available | 2015-11-24T19:12:56Z | - |
| dc.identifier.issn | 0029-7844 | - |
| dc.identifier.uri | https://olympias.lib.uoi.gr/jspui/handle/123456789/21133 | - |
| dc.rights | Default Licence | - |
| dc.subject | Adult | en |
| dc.subject | Case-Control Studies | en |
| dc.subject | Cervical Intraepithelial Neoplasia/*surgery/virology | en |
| dc.subject | Female | en |
| dc.subject | Follow-Up Studies | en |
| dc.subject | Humans | en |
| dc.subject | Logistic Models | en |
| dc.subject | Papillomaviridae/*isolation & purification | en |
| dc.subject | Predictive Value of Tests | en |
| dc.subject | Retrospective Studies | en |
| dc.subject | Risk Assessment | en |
| dc.subject | Sensitivity and Specificity | en |
| dc.subject | Treatment Failure | en |
| dc.subject | Uterine Cervical Neoplasms/*surgery/virology | en |
| dc.subject | Vaginal Smears | en |
| dc.title | Human papillomavirus testing and the outcome of treatment for cervical intraepithelial neoplasia | en |
| heal.type | journalArticle | - |
| heal.type.en | Journal article | en |
| heal.type.el | Άρθρο Περιοδικού | el |
| heal.identifier.secondary | http://www.ncbi.nlm.nih.gov/pubmed/11704177 | - |
| heal.language | en | - |
| heal.access | campus | - |
| heal.recordProvider | Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής | el |
| heal.publicationDate | 2001 | - |
| heal.abstract | OBJECTIVE: To investigate whether human papillomavirus (HPV) testing could be used in the follow-up after large loop excision of the transformation zone (LLETZ) for cervical intraepithelial neoplasia (CIN). METHODS: We performed a retrospective study of 41 women who developed subsequent CIN after LLETZ (group A) and 82 women without CIN for a minimum of 5 years after LLETZ (group B). The first post-treatment cervical smear was retrieved and examined for high-risk HPV deoxyribonucleic acid. The sensitivity, specificity, positive and negative likelihood ratio of HPV testing, first post-treatment Papanicolaou test, and excision margins for the detection of treatment failure were calculated. Multiple logistic regression analysis was also done. RESULTS: The HPV test was positive in 38 of 41 women in group A and 13 of 82 in group B (P <.001). An abnormal cytologic result in the first post-treatment smear was found in 20 of 41 in group A and 11 of 82 in group B (P <.001). Sixteen women in group A and 18 in group B had involved margins (P =.046). Values for the sensitivity, specificity, and positive and negative likelihood ratios of the HPV test were 93%, 84%, 5.8, 0.08; for the Papanicolaou test they were 49%, 87%, 3.9, 0.586; and for margin status they were 39%, 78%, 1.8, 0.782, respectively. Positive HPV test presents significantly high odds ratio for treatment failure (P <.001), independent of cytology and margin status. CONCLUSION: Women who postoperatively have positive HPV testing are at higher risk of treatment failure. This could be performed at the first post-treatment visit and further follow-up could be adjusted accordingly. | en |
| heal.journalName | Obstet Gynecol | en |
| heal.journalType | peer-reviewed | - |
| heal.fullTextAvailability | TRUE | - |
| Appears in Collections: | Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά) - ΙΑΤ | |
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