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https://olympias.lib.uoi.gr/jspui/handle/123456789/21034Full metadata record
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Mantas, C. | en |
| dc.contributor.author | Direskeneli, H. | en |
| dc.contributor.author | Oz, D. | en |
| dc.contributor.author | Yavuz, S. | en |
| dc.contributor.author | Akoglu, T. | en |
| dc.date.accessioned | 2015-11-24T19:12:11Z | - |
| dc.date.available | 2015-11-24T19:12:11Z | - |
| dc.identifier.issn | 0392-856X | - |
| dc.identifier.uri | https://olympias.lib.uoi.gr/jspui/handle/123456789/21034 | - |
| dc.rights | Default Licence | - |
| dc.subject | Actins/blood/genetics | en |
| dc.subject | Adult | en |
| dc.subject | Arthritis, Rheumatoid/blood | en |
| dc.subject | Behcet Syndrome/*blood | en |
| dc.subject | Cell Separation | en |
| dc.subject | Cells, Cultured | en |
| dc.subject | DNA Primers/chemistry | en |
| dc.subject | Female | en |
| dc.subject | Granulocytes/cytology/metabolism | en |
| dc.subject | Humans | en |
| dc.subject | Interleukin-8/*blood/genetics | en |
| dc.subject | Lymphocytes/cytology/metabolism | en |
| dc.subject | Male | en |
| dc.subject | Middle Aged | en |
| dc.subject | Monocytes/cytology/metabolism | en |
| dc.subject | Polymerase Chain Reaction | en |
| dc.subject | RNA, Messenger/biosynthesis | en |
| dc.subject | Sepsis/blood | en |
| dc.title | IL-8 producing cells in patients with Behcet's disease | en |
| heal.type | journalArticle | - |
| heal.type.en | Journal article | en |
| heal.type.el | Άρθρο Περιοδικού | el |
| heal.identifier.secondary | http://www.ncbi.nlm.nih.gov/pubmed/10812500 | - |
| heal.language | en | - |
| heal.access | campus | - |
| heal.recordProvider | Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής | el |
| heal.publicationDate | 2000 | - |
| heal.abstract | OBJECTIVE: IL-8 is thought to be the principal chemokine responsible for neutrophil activation and tissue infiltration in patients with Behcet's disease (BD). In various studies serum levels of IL-8 were reported to be increased. METHODS: IL-8 mRNA was purified from both peripheral whole blood samples and separated lymphocytes, granulocytes and monocytes of patients with BD and compared to that from healthy (HC) and disease controls. IL-8 sequences were revealed by PCR amplification using appropriate sequence-specific primers. mRNA levels were determined semi-quantitatively using an image analyser in comparison with beta-actin. RESULTS: Although the differences did not reach statistical significance, BD patients tended to have higher IL-8 mRNA levels compared to HC in whole blood samples (2.0 +/- 1.4 vs 1.5 +/- 1.2) as well as in their lymphocytes (2.7 +/- 1.6 vs 1.5 +/- 0.9). No differences were observed between BD and HC in monocyte or granulocyte IL-8 mRNA levels. CONCLUSION: Our results suggest that the cellular source of IL-8 is diverse in BD with a possible major contribution by lymphocytes. | en |
| heal.journalName | Clin Exp Rheumatol | en |
| heal.journalType | peer-reviewed | - |
| heal.fullTextAvailability | TRUE | - |
| Appears in Collections: | Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά) - ΙΑΤ | |
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