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| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Danielides, S. | en |
| dc.contributor.author | Mavragani, C. P. | en |
| dc.contributor.author | Katsakoulas, I. | en |
| dc.contributor.author | Zintzaras, E. | en |
| dc.contributor.author | Drosos, A. A. | en |
| dc.contributor.author | Vlachoyiannopoulos, P. G. | en |
| dc.contributor.author | Moutsopoulos, H. M. | en |
| dc.date.accessioned | 2015-11-24T19:10:43Z | - |
| dc.date.available | 2015-11-24T19:10:43Z | - |
| dc.identifier.issn | 1502-7732 | - |
| dc.identifier.uri | https://olympias.lib.uoi.gr/jspui/handle/123456789/20860 | - |
| dc.rights | Default Licence | - |
| dc.subject | Adult | en |
| dc.subject | Aged | en |
| dc.subject | Antibodies, Anti-Idiotypic/*blood | en |
| dc.subject | Autoantibodies/blood | en |
| dc.subject | Case-Control Studies | en |
| dc.subject | Cohort Studies | en |
| dc.subject | Female | en |
| dc.subject | Humans | en |
| dc.subject | Iodide Peroxidase/immunology | en |
| dc.subject | Male | en |
| dc.subject | Middle Aged | en |
| dc.subject | Phenotype | en |
| dc.subject | Scleroderma, Diffuse/blood/*immunology | en |
| dc.subject | Scleroderma, Limited/blood/*immunology | en |
| dc.subject | Thyroid Gland/*immunology | en |
| dc.title | Increased prevalence of anti-thyroid antibodies in patients with limited scleroderma | en |
| heal.type | journalArticle | - |
| heal.type.en | Journal article | en |
| heal.type.el | Άρθρο Περιοδικού | el |
| heal.identifier.primary | 10.3109/03009742.2010.549837 | - |
| heal.identifier.secondary | http://www.ncbi.nlm.nih.gov/pubmed/21417550 | - |
| heal.identifier.secondary | http://informahealthcare.com/doi/abs/10.3109/03009742.2010.549837 | - |
| heal.language | en | - |
| heal.access | campus | - |
| heal.recordProvider | Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής | el |
| heal.publicationDate | 2011 | - |
| heal.abstract | OBJECTIVES: Thyroid dysfunction in the setting of systemic sclerosis (SSc) has been described previously. We aimed to determine the prevalence of anti-thyroid antibodies (ATA) in a large SSc cohort and to ascertain whether they are associated with distinct clinical phenotypes. METHODS: A total of 138 patients with SSc [46 with diffuse (dSSc) and 92 with limited scleroderma (lSSc)] and 100 healthy controls (HC) were tested for the presence of ATA [anti-thyroglobulin (anti-Tg) and anti-thyroid peroxidase (anti-TPO) antibodies] using a commercial enzyme-linked immunosorbent assay (ELISA). Clinical and serological data were recorded. RESULTS: An increased prevalence of anti-TPO but not anti-Tg antibodies was detected in patients with SSc compared to HC (27.5% vs. 14%, p = 0.016). Of note, a statistically significant increase of anti-TPO was detected only in patients with lSSc compared to HC (32.6% vs. 14%, p = 0.003). No correlations with other clinical features were detected. CONCLUSIONS: An increased prevalence of anti-TPO antibodies was identified in patients with lSSc. We propose that ATA testing should be offered to this subgroup of patients. | en |
| heal.journalName | Scandinavian Journal of Rheumatology | en |
| heal.journalType | peer-reviewed | - |
| heal.fullTextAvailability | TRUE | - |
| Appears in Collections: | Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά) - ΙΑΤ | |
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