Please use this identifier to cite or link to this item:
https://olympias.lib.uoi.gr/jspui/handle/123456789/20856
Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Vairaktaris, E. | en |
dc.contributor.author | Goutzanis, L. | en |
dc.contributor.author | Kalokerinos, G. | en |
dc.contributor.author | Vassiliou, S. | en |
dc.contributor.author | Spyridonidou, S. | en |
dc.contributor.author | Avgoustidis, D. | en |
dc.contributor.author | Strantzias, P. | en |
dc.contributor.author | Lazaris, A. | en |
dc.contributor.author | Papageorgiou, G. | en |
dc.contributor.author | Ragos, V. | en |
dc.contributor.author | Yapijakis, C. | en |
dc.contributor.author | Patsouris, E. | en |
dc.date.accessioned | 2015-11-24T19:10:41Z | - |
dc.date.available | 2015-11-24T19:10:41Z | - |
dc.identifier.issn | 1010-5182 | - |
dc.identifier.uri | https://olympias.lib.uoi.gr/jspui/handle/123456789/20856 | - |
dc.rights | Default Licence | - |
dc.subject | 4-Nitroquinoline-1-oxide/adverse effects | en |
dc.subject | Animals | en |
dc.subject | Biopsy | en |
dc.subject | Carcinogens | en |
dc.subject | Carcinoma, Squamous Cell/chemically induced/genetics/pathology | en |
dc.subject | Diabetes Mellitus, Experimental/*complications/genetics | en |
dc.subject | Female | en |
dc.subject | Gene Expression Regulation, Enzymologic/genetics | en |
dc.subject | Gene Expression Regulation, Neoplastic/genetics | en |
dc.subject | Immunohistochemistry | en |
dc.subject | JNK Mitogen-Activated Protein Kinases/genetics | en |
dc.subject | Mouth Mucosa/drug effects/pathology | en |
dc.subject | Mouth Neoplasms/*chemically induced/genetics/pathology | en |
dc.subject | Neoplasm Staging | en |
dc.subject | Precancerous Conditions/chemically induced/genetics/pathology | en |
dc.subject | Proto-Oncogene Proteins c-jun/*genetics | en |
dc.subject | Random Allocation | en |
dc.subject | Rats | en |
dc.subject | Rats, Sprague-Dawley | en |
dc.subject | Risk Factors | en |
dc.title | Increased risk of oral cancer in diabetic animals is not associated with c-jun activation pathway | en |
heal.type | journalArticle | - |
heal.type.en | Journal article | en |
heal.type.el | Άρθρο Περιοδικού | el |
heal.identifier.primary | 10.1016/j.jcms.2007.05.006 | - |
heal.identifier.secondary | http://www.ncbi.nlm.nih.gov/pubmed/18023197 | - |
heal.identifier.secondary | http://ac.els-cdn.com/S1010518207000972/1-s2.0-S1010518207000972-main.pdf?_tid=35605916b2da45cd9d664b7a56d68146&acdnat=1332845835_cd46e99863b50db9a6ced7e83df6aebd | - |
heal.language | en | - |
heal.access | campus | - |
heal.recordProvider | Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής | el |
heal.publicationDate | 2007 | - |
heal.abstract | PURPOSE: The expression of oncogenic protein c-jun was investigated in an experimental model of chemically induced carcinogenesis in normal and diabetic (type I) Sprague-Dawley rats. MATERIAL AND METHODS: Thirteen diabetic and twelve normal rats developed cancer after 4-nitroquinoline-N-oxide treatment, while six diabetic and six normal animals were used as controls. The biopsies were classified pathologically from oral mucosal dysplasia to moderately differentiated oral squamous cell carcinoma (OSCC) and studied immunohistochemically using monoclonal antibody against c-jun protein. RESULTS: Higher c-jun levels were observed in non-cancerous and precancerous stages of normal rats compared with diabetic rats, while in different tumour stages, the expression of c-jun was practically identical for both groups. CONCLUSION: It seems that diabetes does not affect the c-jun N-terminal kinase (JNK)/c-jun pathway. | en |
heal.journalName | J Craniomaxillofac Surg | en |
heal.journalType | peer-reviewed | - |
heal.fullTextAvailability | TRUE | - |
Appears in Collections: | Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά) - ΙΑΤ |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
Vairaktaris-2007-Increased risk of or.pdf | 371.05 kB | Adobe PDF | View/Open Request a copy |
This item is licensed under a Creative Commons License