Please use this identifier to cite or link to this item: https://olympias.lib.uoi.gr/jspui/handle/123456789/20547
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dc.contributor.authorVagenakis, G. A.en
dc.contributor.authorHyphantis, T. N.en
dc.contributor.authorPapageorgiou, C.en
dc.contributor.authorProtonatariou, A.en
dc.contributor.authorSgourou, A.en
dc.contributor.authorDimopoulos, P. A.en
dc.contributor.authorMavreas, V.en
dc.contributor.authorVagenakis, A. G.en
dc.contributor.authorGeorgopoulos, N. A.en
dc.date.accessioned2015-11-24T19:08:34Z-
dc.date.available2015-11-24T19:08:34Z-
dc.identifier.issn0091-2174-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/20547-
dc.rightsDefault Licence-
dc.subjectAdulten
dc.subjectAtrophy/pathologyen
dc.subjectBrain/pathologyen
dc.subjectDiagnostic and Statistical Manual of Mental Disordersen
dc.subjectFemaleen
dc.subjectHumansen
dc.subjectHypogonadism/complications/diagnosisen
dc.subjectHypothalamus/pathologyen
dc.subjectKallmann Syndrome/*complications/diagnosisen
dc.subjectMmpien
dc.subjectMagnetic Resonance Imagingen
dc.subjectOlfaction Disorders/complications/diagnosisen
dc.subjectOlfactory Bulb/pathologyen
dc.subjectPituitary Gland, Anterior/pathologyen
dc.subjectQuestionnairesen
dc.subjectSchizophrenia/*complications/diagnosisen
dc.titleKallmann's syndrome and schizophreniaen
heal.typejournalArticle-
heal.type.enJournal articleen
heal.type.elΆρθρο Περιοδικούel
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/15825586-
heal.languageen-
heal.accesscampus-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.publicationDate2004-
heal.abstractOBJECTIVE: Kallmann's Syndrome is a heritable disorder characterized by the association of hypogonadotropic hypogonadism and anosmia or hyposmia. A common pathogenesis for KS and schizophrenia had been proposed based on shared pathologies of these two disorders, although no such clinical associations have ever been reported. METHOD: We report a 35 year old man with schizophrenia and Kallmann's Syndrome. The patient presented with signs and symptoms of hypogonadism, severe hyposmia and normal endocrine functions of the anterior pituitary. Hyposmia has been attributed to the absence of the olfactory bulbs and tracts and atrophy of the olfactory gyri, but normal olfactory mucosa. The patient presented with paranoid schizophrenia with persecutory delusions, auditory hallucinations, thought disorder, depersonalization, and gradual but marked global deterioration. RESULTS: Psychiatric evaluation revealed an entirely different psychopathological and personality profile between the patient and the six other Kallmann patients studied. Cycle sequencing analysis revealed a normal sequence of all 14 exons of the KAL gene. In conclusion, based on the presented case, Kallmann's Syndrome and schizophrenia represent a rare clinical association rather than a syndrome with a common pathogenesis, which if present should be confined to the olfactory dysfunction.en
heal.journalNameInt J Psychiatry Meden
heal.journalTypepeer-reviewed-
heal.fullTextAvailabilityTRUE-
Appears in Collections:Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά) - ΙΑΤ

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