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| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Papadimitriou, C. S. | en |
| dc.contributor.author | Datseris, G. | en |
| dc.contributor.author | Costopoulos, J. S. | en |
| dc.contributor.author | Bai, M. K. | en |
| dc.contributor.author | Ioachim-Velogianni, E. | en |
| dc.contributor.author | Katsouyannopoulos, V. | en |
| dc.date.accessioned | 2015-11-24T19:08:12Z | - |
| dc.date.available | 2015-11-24T19:08:12Z | - |
| dc.identifier.issn | 0344-0338 | - |
| dc.identifier.uri | https://olympias.lib.uoi.gr/jspui/handle/123456789/20507 | - |
| dc.rights | Default Licence | - |
| dc.subject | Adult | en |
| dc.subject | Aged | en |
| dc.subject | Aged, 80 and over | en |
| dc.subject | Antibodies, Monoclonal | en |
| dc.subject | Carcinoma/chemistry/*pathology | en |
| dc.subject | Colorectal Neoplasms/chemistry/*pathology | en |
| dc.subject | Female | en |
| dc.subject | Humans | en |
| dc.subject | Langerhans Cells/*pathology | en |
| dc.subject | Male | en |
| dc.subject | Middle Aged | en |
| dc.subject | S100 Proteins/analysis | en |
| dc.subject | Stomach Neoplasms/chemistry/*pathology | en |
| dc.subject | T-Lymphocytes, Helper-Inducer/*pathology | en |
| dc.subject | T-Lymphocytes, Regulatory/*pathology | en |
| dc.title | Langerhans cells and lymphocyte subsets in human gastrointestinal carcinomas. An immunohistological study on frozen sections | en |
| heal.type | journalArticle | - |
| heal.type.en | Journal article | en |
| heal.type.el | Άρθρο Περιοδικού | el |
| heal.identifier.secondary | http://www.ncbi.nlm.nih.gov/pubmed/1300611 | - |
| heal.language | en | - |
| heal.access | campus | - |
| heal.recordProvider | Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής | el |
| heal.publicationDate | 1992 | - |
| heal.abstract | In an immunohistochemical study of 38 human gastric and 40 human colonic carcinomas Langerhans cells, suppressor and helper lymphocytes were identified on frozen sections by using anti-CD1, anti-CD8 and anti-CD4 monoclonal antibodies. Tumours were divided into those with few (< 3 per high power field) and those with many (> 3 per high power field) Langerhans cells as well as into those with high number of CD4 and CD8 cells (> 30 per high power field). No significant difference in the number of Langerhans cells regarding histologic types, degree of differentiation and metastatic/non-metastatic groups of either gastric or colonic carcinomas was found. On the contrary the numbers of Langerhans cells related significantly (p < 0.05) to density of T-cell and especially CD4 cell infiltrations of gastric and colonic carcinomas. This finding supports the role of Langerhans cells as antigen presenting cells and their involvement in T-cell activation against neoplastic cells of human gastrointestinal carcinomas. | en |
| heal.journalName | Pathol Res Pract | en |
| heal.journalType | peer-reviewed | - |
| heal.fullTextAvailability | TRUE | - |
| Appears in Collections: | Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά) - ΙΑΤ | |
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