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  4. Τμήμα Ιατρικής
  5. Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά) - ΙΑΤ
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Please use this identifier to cite or link to this item: https://olympias.lib.uoi.gr/jspui/handle/123456789/20317
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dc.contributor.authorPamecha, V.en
dc.contributor.authorGlantzounis, G.en
dc.contributor.authorDavies, N.en
dc.contributor.authorFusai, G.en
dc.contributor.authorSharma, D.en
dc.contributor.authorDavidson, B.en
dc.date.accessioned2015-11-24T19:06:14Z-
dc.date.available2015-11-24T19:06:14Z-
dc.identifier.issn1534-4681-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/20317-
dc.rightsDefault Licence-
dc.subjectAdulten
dc.subjectAgeden
dc.subjectAged, 80 and overen
dc.subjectAntineoplastic Agents/administration & dosageen
dc.subjectColorectal Neoplasms/pathology/surgery/*therapyen
dc.subject*Embolization, Therapeuticen
dc.subjectFemaleen
dc.subjectHepatectomyen
dc.subjectHumansen
dc.subjectLiver Neoplasms/secondary/surgery/*therapyen
dc.subjectLiver Regenerationen
dc.subjectMaleen
dc.subjectMiddle Ageden
dc.subjectNeoplasm Recurrence, Localen
dc.subject*Portal Veinen
dc.subjectPreoperative Careen
dc.subjectSurvival Analysisen
dc.titleLong-term survival and disease recurrence following portal vein embolisation prior to major hepatectomy for colorectal metastasesen
heal.typejournalArticle-
heal.type.enJournal articleen
heal.type.elΆρθρο Περιοδικούel
heal.identifier.primary10.1245/s10434-008-0269-4-
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/19130138-
heal.identifier.secondaryhttp://www.springerlink.com/content/kn58m2221g831312/fulltext.pdf-
heal.languageen-
heal.accesscampus-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.publicationDate2009-
heal.abstractBACKGROUND: Portal vein embolisation (PVE) can be used to increase the remnant liver parenchyma volume before major hepatectomy but may stimulate tumour growth. The pattern of disease recurrence and long-term survival has not been adequately addressed. METHODS: Over a period of 7 years 36 patients underwent preoperative PVE before resection of four or more liver segments for colorectal cancer (CRC) liver metastases. PVE was performed when the future liver remnant (FLR) assessed by magnetic resonance imaging (MRI) scan volumetry was less than 30%. Disease-free and overall survival was compared with a control group (65 patients) undergoing extended right/right hepatectomy for CRC metastases without PVE during the same time period. RESULTS: PVE was successful in all patients. PVE increased the median FLR volume by 37% [295 ml (22%) to 404 ml (32%), p < 0.0001]. 61% of patients undergoing PVE proceeded to liver resection (n = 22). Twelve patients (33%) developed disease progression following PVE. The 5-year survival after liver resection with PVE was 25%, compared with 50% without PVE. The 5-year disease-free survival was 30% post PVE and 50% without PVE. CONCLUSION: We conclude that PVE significantly increases the future liver remnant. Only two-thirds of patients proceed to resection because of disease progression. Long-term survival is less than in patients who do not require PVE. The effect of PVE on tumour growth requires investigation.en
heal.journalNameAnn Surg Oncolen
heal.journalTypepeer-reviewed-
heal.fullTextAvailabilityTRUE-
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