Please use this identifier to cite or link to this item: https://olympias.lib.uoi.gr/jspui/handle/123456789/20305
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dc.contributor.authorGiapros, V.en
dc.contributor.authorDrougia, A.en
dc.contributor.authorAsproudis, I.en
dc.contributor.authorTheocharis, P.en
dc.contributor.authorAndronikou, S.en
dc.date.accessioned2015-11-24T19:06:09Z-
dc.date.available2015-11-24T19:06:09Z-
dc.identifier.issn1872-6232-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/20305-
dc.rightsDefault Licence-
dc.subjectAdulten
dc.subjectChronic Diseaseen
dc.subjectDuctus Arteriosus, Patenten
dc.subjectEnterocolitis, Necrotizing/epidemiologyen
dc.subjectFemaleen
dc.subjectGestational Ageen
dc.subjectGreeceen
dc.subjectHumansen
dc.subjectInfant, Low Birth Weighten
dc.subjectInfant, Newbornen
dc.subjectInfant, Prematureen
dc.subjectInfant, Premature, Diseases/epidemiologyen
dc.subjectIntensive Care Units, Neonatalen
dc.subjectLung Diseases/*complications/epidemiologyen
dc.subjectMaleen
dc.subjectMaternal Ageen
dc.subjectPregnancyen
dc.subjectPregnancy Complications/epidemiologyen
dc.subjectPregnancy, Multipleen
dc.subjectRespiratory Distress Syndrome, Newbornen
dc.subjectRetinopathy of Prematurity/*epidemiology/*etiologyen
dc.subjectRetrospective Studiesen
dc.subjectRisk Factorsen
dc.titleLow gestational age and chronic lung disease are synergistic risk factors for retinopathy of prematurityen
heal.typejournalArticle-
heal.type.enJournal articleen
heal.type.elΆρθρο Περιοδικούel
heal.identifier.primary10.1016/j.earlhumdev.2011.05.003-
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/21621351-
heal.identifier.secondaryhttp://ac.els-cdn.com/S0378378211001861/1-s2.0-S0378378211001861-main.pdf?_tid=e443788e08b6a3c3d8f5f3718831d395&acdnat=1332917042_da8421e72e79ca778fd04603ad5f5898-
heal.languageen-
heal.accesscampus-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.publicationDate2011-
heal.abstractAIMS: This retrospective, population based study was designed to investigate risk factors for development of retinopathy of prematurity (ROP) and their possible interrelationships, in neonates of gestational age (GA) <32 weeks born in a well-defined geographical region. STUDY DESIGN-SUBJECTS: The study population included all preterm infants born alive with GA 24-32 weeks in Northwestern Greece during a 9-year period and hospitalised in the regional neonatal intensive care unit (NICU). OUTCOME MEASUREMENTS: The association was assessed of the presence of ROP with maternal factors: age, pathology of pregnancy, in-vitro fertilisation, multiple gestation, mode of delivery, perinatal factors: gender, antenatal steroids, transportation, resuscitation, GA, birth weight (BW), small for GA status and postnatal morbidity: chronic lung disease (CLD), intraventricular haemorrhage (IVH), necrotizing enterocolitis (NEC), respiratory distress syndrome (RDS), maximum O(2) needs, hypoxic/hyperoxic episodes, patent ductus arteriosus (PDA), sepsis, using multiple logistic regression analysis. RESULTS: Of 189 infants without congenital anomalies born at GA 24-32 weeks ROP was diagnosed in 24 (12.7%) (>grade 2: 6). Logistic regression analysis showed ROP to be strongly associated with GA, odds ratio (OR) 2.1, confidence interval (CI) 1.3-3.3, p<0.01 and CLD, OR 10.2, CI 2.3-44, p<0.01, respectively, independent of confounding factors. By estimating interaction on an additive scale it was shown that the combined risk effect of GA and CLD was larger than the sum of the individual risk effects, implying synergistic effect. CONCLUSIONS: ROP was closely and independently related to both low GA and the diagnosis of CLD, which were interrelated in the development of ROP.en
heal.journalNameEarly Hum Deven
heal.journalTypepeer-reviewed-
heal.fullTextAvailabilityTRUE-
Appears in Collections:Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά) - ΙΑΤ

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