Please use this identifier to cite or link to this item: https://olympias.lib.uoi.gr/jspui/handle/123456789/20293
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dc.contributor.authorPapaxoinis, G.en
dc.contributor.authorFountzilas, G.en
dc.contributor.authorRontogianni, D.en
dc.contributor.authorDimopoulos, M. A.en
dc.contributor.authorPavlidis, N.en
dc.contributor.authorTsatalas, C.en
dc.contributor.authorPectasides, D.en
dc.contributor.authorXiros, N.en
dc.contributor.authorEconomopoulos, T.en
dc.date.accessioned2015-11-24T19:06:04Z-
dc.date.available2015-11-24T19:06:04Z-
dc.identifier.issn1569-8041-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/20293-
dc.rightsDefault Licence-
dc.subjectAdolescenten
dc.subjectAdulten
dc.subjectAgeden
dc.subjectAged, 80 and overen
dc.subjectAnalysis of Varianceen
dc.subjectChemotherapy, Adjuvanten
dc.subjectDisease-Free Survivalen
dc.subjectFemaleen
dc.subjectGreece/epidemiologyen
dc.subjectHumansen
dc.subjectKaplan-Meier Estimateen
dc.subjectLung Neoplasms/diagnosis/therapyen
dc.subjectLymphoma, B-Cell, Marginal Zone/*diagnosis/drugen
dc.subjecttherapy/epidemiology/pathology/surgery/*therapyen
dc.subjectMaleen
dc.subjectMiddle Ageden
dc.subjectNeoplasm Stagingen
dc.subjectParotid Neoplasms/diagnosis/therapyen
dc.subjectPrognosisen
dc.subjectProportional Hazards Modelsen
dc.subjectRegistriesen
dc.subjectRetrospective Studiesen
dc.subjectRisk Factorsen
dc.subjectSeverity of Illness Indexen
dc.subjectStomach Neoplasms/diagnosis/therapyen
dc.titleLow-grade mucosa-associated lymphoid tissue lymphoma: a retrospective analysis of 97 patients by the Hellenic Cooperative Oncology Group (HeCOG)en
heal.typejournalArticle-
heal.type.enJournal articleen
heal.type.elΆρθρο Περιοδικούel
heal.identifier.primary10.1093/annonc/mdm529-
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/18156143-
heal.identifier.secondaryhttp://annonc.oxfordjournals.org/content/19/4/780.full.pdf-
heal.languageen-
heal.accesscampus-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.publicationDate2008-
heal.abstractBACKGROUND: The aim was to examine characteristics and treatment results of patients with mucosa-associated lymphoid tissue (MALT) non-Hodgkin's lymphomas. PATIENTS AND METHODS: Epidemiological and clinical features of 97 patients with MALT lymphoma from the Hellenic Cooperative Oncology Group registry were analysed retrospectively for their prognostic significance in progression-free survival (PFS) and overall survival (OS). Comparisons were made between patients with gastric and nongastric sites of primary lymphoma and between different therapeutic modalities. RESULTS: Sixty-five patients presented with gastric and 32 with nongastric lymphomas. The most frequent locations of nongastric lymphomas were the bowel, lung and parotid. Gastric lymphomas occurred more frequently in males and younger patients compared with nongastric lymphomas. Seventy-four per cent of patients had early (Ann Arbor stages I-II) and 26% had advanced (stages III-IV) disease. The median PFS for the entire population was 44 months. At 5 years, 47% of patients were progression free and the OS rate was 80%. The most reliable prognostic factor for PFS and OS was the Ann Arbor stage; 5-year PFS was 67% versus 13% and 5-year OS 91% versus 51% for patients with early versus advanced disease, respectively (P < 0.001). Of the patients treated with chemotherapy only, 87% achieved an objective response and 71% complete response. Surgery did not offer survival benefit compared with chemotherapy in localised gastric lymphoma. CONCLUSION: MALT lymphomas represent a distinct disease entity with widespread extranodal origin, indolent clinical course and high chemosensitivity. Ann Arbor stage was the most reliable prognostic and predictive factor.en
heal.journalNameAnn Oncolen
heal.journalTypepeer-reviewed-
heal.fullTextAvailabilityTRUE-
Appears in Collections:Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά) - ΙΑΤ

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