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Please use this identifier to cite or link to this item: https://olympias.lib.uoi.gr/jspui/handle/123456789/20147
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dc.contributor.authorGonzalez, C. A.en
dc.contributor.authorJakszyn, P.en
dc.contributor.authorPera, G.en
dc.contributor.authorAgudo, A.en
dc.contributor.authorBingham, S.en
dc.contributor.authorPalli, D.en
dc.contributor.authorFerrari, P.en
dc.contributor.authorBoeing, H.en
dc.contributor.authordel Giudice, G.en
dc.contributor.authorPlebani, M.en
dc.contributor.authorCarneiro, F.en
dc.contributor.authorNesi, G.en
dc.contributor.authorBerrino, F.en
dc.contributor.authorSacerdote, C.en
dc.contributor.authorTumino, R.en
dc.contributor.authorPanico, S.en
dc.contributor.authorBerglund, G.en
dc.contributor.authorSiman, H.en
dc.contributor.authorNyren, O.en
dc.contributor.authorHallmans, G.en
dc.contributor.authorMartinez, C.en
dc.contributor.authorDorronsoro, M.en
dc.contributor.authorBarricarte, A.en
dc.contributor.authorNavarro, C.en
dc.contributor.authorQuiros, J. R.en
dc.contributor.authorAllen, N. C.en
dc.contributor.authorKey, T. J.en
dc.contributor.authorDay, N. E.en
dc.contributor.authorLinseisen, J.en
dc.contributor.authorNagel, G.en
dc.contributor.authorBergmann, M. M.en
dc.contributor.authorOvervad, K.en
dc.contributor.authorJensen, M. K.en
dc.contributor.authorTjonneland, A.en
dc.contributor.authorOlsen, A.en
dc.contributor.authorBueno-de-Mesquita, H. B.en
dc.contributor.authorOcke, M.en
dc.contributor.authorPeeters, P. H.en
dc.contributor.authorNumans, M. E.en
dc.contributor.authorClavel-Chapelon, F.en
dc.contributor.authorBoutron-Ruault, M. C.en
dc.contributor.authorTrichopoulou, A.en
dc.contributor.authorPsaltopoulou, T.en
dc.contributor.authorRoukos, D.en
dc.contributor.authorLund, E.en
dc.contributor.authorHemon, B.en
dc.contributor.authorKaaks, R.en
dc.contributor.authorNorat, T.en
dc.contributor.authorRiboli, E.en
dc.date.accessioned2015-11-24T19:05:07Z-
dc.date.available2015-11-24T19:05:07Z-
dc.identifier.issn1460-2105-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/20147-
dc.rightsDefault Licence-
dc.subjectAdenocarcinoma/*epidemiology/etiology/microbiologyen
dc.subjectAdulten
dc.subjectAgeden
dc.subjectCardiaen
dc.subjectCase-Control Studiesen
dc.subjectConfidence Intervalsen
dc.subjectEsophageal Neoplasms/*epidemiology/etiology/microbiologyen
dc.subjectEurope/epidemiologyen
dc.subjectFemaleen
dc.subjectFollow-Up Studiesen
dc.subject*Food Habitsen
dc.subjectHelicobacter Infections/*complications/microbiologyen
dc.subject*Helicobacter pylorien
dc.subjectHumansen
dc.subjectIncidenceen
dc.subjectLife Styleen
dc.subjectMaleen
dc.subject*Meaten
dc.subjectMiddle Ageden
dc.subjectOdds Ratioen
dc.subjectProportional Hazards Modelsen
dc.subjectProspective Studiesen
dc.subjectQuestionnairesen
dc.subjectRisk Assessmenten
dc.subjectRisk Factorsen
dc.subjectStomach Neoplasms/*epidemiology/etiology/microbiologyen
dc.titleMeat intake and risk of stomach and esophageal adenocarcinoma within the European Prospective Investigation Into Cancer and Nutrition (EPIC)en
heal.typejournalArticle-
heal.type.enJournal articleen
heal.type.elΆρθρο Περιοδικούel
heal.identifier.primary10.1093/jnci/djj071-
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/16507831-
heal.identifier.secondaryhttp://jnci.oxfordjournals.org/content/98/5/345.full.pdf-
heal.languageen-
heal.accesscampus-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.publicationDate2006-
heal.abstractBACKGROUND: Dietary factors are thought to have an important role in gastric and esophageal carcinogenesis, but evidence from cohort studies for such a role is lacking. We examined the risks of gastric cancer and esophageal adenocarcinoma associated with meat consumption within the European Prospective Investigation Into Cancer and Nutrition (EPIC) cohort. METHODS: A total of 521,457 men and women aged 35-70 years in 10 European countries participated in the EPIC cohort. Dietary and lifestyle information was collected at recruitment. Cox proportional hazard models were used to examine associations between meat intake and risks of cardia and gastric non-cardia cancers and esophageal adenocarcinoma. Data from a calibration substudy were used to correct hazard ratios (HRs) and 95% confidence intervals (CIs) for diet measurement errors. In a nested case-control study, we examined interactions between Helicobacter pylori infection status (i.e., plasma H. pylori antibodies) and meat intakes. All statistical tests were two-sided. RESULTS: During a mean follow-up of 6.5 years, 330 gastric adenocarcinoma and 65 esophageal adenocarcinomas were diagnosed. Gastric non-cardia cancer risk was statistically significantly associated with intakes of total meat (calibrated HR per 100-g/day increase = 3.52; 95% CI = 1.96 to 6.34), red meat (calibrated HR per 50-g/day increase = 1.73; 95% CI = 1.03 to 2.88), and processed meat (calibrated HR per 50-g/day increase = 2.45; 95% CI = 1.43 to 4.21). The association between the risk of gastric non-cardia cancer and total meat intake was especially large in H. pylori-infected subjects (odds ratio per 100-g/day increase = 5.32; 95% CI = 2.10 to 13.4). Intakes of total, red, or processed meat were not associated with the risk of gastric cardia cancer. A positive but non-statistically significant association was observed between esophageal adenocarcinoma cancer risk and total and processed meat intake in the calibrated model. In this study population, the absolute risk of development of gastric adenocarcinoma within 10 years for a study subject aged 60 years was 0.26% for the lowest quartile of total meat intake and 0.33% for the highest quartile of total meat intake. CONCLUSION: Total, red, and processed meat intakes were associated with an increased risk of gastric non-cardia cancer, especially in H. pylori antibody-positive subjects, but not with cardia gastric cancer.en
heal.journalNameJ Natl Cancer Insten
heal.journalTypepeer-reviewed-
heal.fullTextAvailabilityTRUE-
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