Please use this identifier to cite or link to this item: https://olympias.lib.uoi.gr/jspui/handle/123456789/20084
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dc.contributor.authorKarassa, F. B.en
dc.contributor.authorMatsagas, M. I.en
dc.contributor.authorSchmidt, W. A.en
dc.contributor.authorIoannidis, J. P.en
dc.date.accessioned2015-11-24T19:04:40Z-
dc.date.available2015-11-24T19:04:40Z-
dc.identifier.issn1539-3704-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/20084-
dc.rightsDefault Licence-
dc.subjectAdulten
dc.subjectAgeden
dc.subjectBiopsyen
dc.subjectFemaleen
dc.subjectGiant Cell Arteritis/*ultrasonographyen
dc.subjectHumansen
dc.subjectMaleen
dc.subjectMiddle Ageden
dc.subjectROC Curveen
dc.subjectReference Standardsen
dc.subjectResearch Design/standardsen
dc.subjectSensitivity and Specificityen
dc.subjectTemporal Arteries/*ultrasonographyen
dc.subjectUltrasonography/standardsen
dc.titleMeta-analysis: test performance of ultrasonography for giant-cell arteritisen
heal.typejournalArticle-
heal.type.enJournal articleen
heal.type.elΆρθρο Περιοδικούel
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/15738455-
heal.languageen-
heal.accesscampus-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.publicationDate2005-
heal.abstractBACKGROUND: Giant-cell arteritis is a diagnostic challenge. PURPOSE: To determine the diagnostic performance of ultrasonography for giant-cell arteritis. DATA SOURCES: Studies published up to April 2004 in the MEDLINE, EMBASE, and Cochrane databases; reference lists; and direct contact with investigators. STUDY SELECTION: Studies in any language that examined temporal artery ultrasonography for diagnosis of giant-cell arteritis, enrolled at least 5 patients, and used biopsy or the American College of Rheumatology (ACR) criteria as the reference standard. DATA EXTRACTION: Two reviewers independently graded methodologic quality and abstracted data on sensitivity and specificity of ultrasonography for giant-cell arteritis. Diagnostic performance was determined for the halo sign, stenosis, or occlusion and for any of these ultrasonographic abnormalities. DATA SYNTHESIS: Weighted sensitivity and specificity estimates and summary receiver-operating characteristic (ROC) curve analysis were used. Twenty-three studies, involving a total of 2036 patients, met the inclusion criteria. The weighted sensitivity and specificity of the halo sign were 69% (95% CI, 57% to 79%) and 82% (CI, 75% to 87%), respectively, compared with biopsy and 55% (CI, 36% to 73%) and 94% (CI, 82% to 98%), respectively, compared with ACR criteria. Stenosis or occlusion was an almost equally sensitive marker compared with either biopsy (sensitivity, 68% [CI, 49% to 82%]) or ACR criteria (sensitivity, 66% [CI, 32% to 89%]). Consideration of any vessel abnormality nonsignificantly improved diagnostic performance compared with ACR criteria. Between-study heterogeneity was significant, but summary ROC curves were consistent with weighted estimates. When the pretest probability of giant-cell arteritis is 10%, negative results on ultrasonography practically exclude the disease (post-test probability, 2% to 5% for various analyses). LIMITATIONS: The primary studies were small and of modest quality and had considerable heterogeneity. CONCLUSION: Ultrasonography may be helpful in diagnosing giant-cell arteritis, but cautious interpretation of the test results based on clinical presentation and pretest probability of the disease is imperative.en
heal.journalNameAnn Intern Meden
heal.journalTypepeer-reviewed-
heal.fullTextAvailabilityTRUE-
Appears in Collections:Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά) - ΙΑΤ

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