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DC Field | Value | Language |
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dc.contributor.author | Karassa, F. B. | en |
dc.contributor.author | Matsagas, M. I. | en |
dc.contributor.author | Schmidt, W. A. | en |
dc.contributor.author | Ioannidis, J. P. | en |
dc.date.accessioned | 2015-11-24T19:04:40Z | - |
dc.date.available | 2015-11-24T19:04:40Z | - |
dc.identifier.issn | 1539-3704 | - |
dc.identifier.uri | https://olympias.lib.uoi.gr/jspui/handle/123456789/20084 | - |
dc.rights | Default Licence | - |
dc.subject | Adult | en |
dc.subject | Aged | en |
dc.subject | Biopsy | en |
dc.subject | Female | en |
dc.subject | Giant Cell Arteritis/*ultrasonography | en |
dc.subject | Humans | en |
dc.subject | Male | en |
dc.subject | Middle Aged | en |
dc.subject | ROC Curve | en |
dc.subject | Reference Standards | en |
dc.subject | Research Design/standards | en |
dc.subject | Sensitivity and Specificity | en |
dc.subject | Temporal Arteries/*ultrasonography | en |
dc.subject | Ultrasonography/standards | en |
dc.title | Meta-analysis: test performance of ultrasonography for giant-cell arteritis | en |
heal.type | journalArticle | - |
heal.type.en | Journal article | en |
heal.type.el | Άρθρο Περιοδικού | el |
heal.identifier.secondary | http://www.ncbi.nlm.nih.gov/pubmed/15738455 | - |
heal.language | en | - |
heal.access | campus | - |
heal.recordProvider | Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής | el |
heal.publicationDate | 2005 | - |
heal.abstract | BACKGROUND: Giant-cell arteritis is a diagnostic challenge. PURPOSE: To determine the diagnostic performance of ultrasonography for giant-cell arteritis. DATA SOURCES: Studies published up to April 2004 in the MEDLINE, EMBASE, and Cochrane databases; reference lists; and direct contact with investigators. STUDY SELECTION: Studies in any language that examined temporal artery ultrasonography for diagnosis of giant-cell arteritis, enrolled at least 5 patients, and used biopsy or the American College of Rheumatology (ACR) criteria as the reference standard. DATA EXTRACTION: Two reviewers independently graded methodologic quality and abstracted data on sensitivity and specificity of ultrasonography for giant-cell arteritis. Diagnostic performance was determined for the halo sign, stenosis, or occlusion and for any of these ultrasonographic abnormalities. DATA SYNTHESIS: Weighted sensitivity and specificity estimates and summary receiver-operating characteristic (ROC) curve analysis were used. Twenty-three studies, involving a total of 2036 patients, met the inclusion criteria. The weighted sensitivity and specificity of the halo sign were 69% (95% CI, 57% to 79%) and 82% (CI, 75% to 87%), respectively, compared with biopsy and 55% (CI, 36% to 73%) and 94% (CI, 82% to 98%), respectively, compared with ACR criteria. Stenosis or occlusion was an almost equally sensitive marker compared with either biopsy (sensitivity, 68% [CI, 49% to 82%]) or ACR criteria (sensitivity, 66% [CI, 32% to 89%]). Consideration of any vessel abnormality nonsignificantly improved diagnostic performance compared with ACR criteria. Between-study heterogeneity was significant, but summary ROC curves were consistent with weighted estimates. When the pretest probability of giant-cell arteritis is 10%, negative results on ultrasonography practically exclude the disease (post-test probability, 2% to 5% for various analyses). LIMITATIONS: The primary studies were small and of modest quality and had considerable heterogeneity. CONCLUSION: Ultrasonography may be helpful in diagnosing giant-cell arteritis, but cautious interpretation of the test results based on clinical presentation and pretest probability of the disease is imperative. | en |
heal.journalName | Ann Intern Med | en |
heal.journalType | peer-reviewed | - |
heal.fullTextAvailability | TRUE | - |
Appears in Collections: | Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά) - ΙΑΤ |
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