Please use this identifier to cite or link to this item: https://olympias.lib.uoi.gr/jspui/handle/123456789/20074
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dc.contributor.authorMilionis, H. J.en
dc.contributor.authorFlorentin, M.en
dc.contributor.authorGiannopoulos, S.en
dc.date.accessioned2015-11-24T19:04:37Z-
dc.date.available2015-11-24T19:04:37Z-
dc.identifier.issn1092-8529-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/20074-
dc.rightsDefault Licence-
dc.subjectAlzheimer Disease/etiology/metabolism/*pathologyen
dc.subjectAtherosclerosis/complicationsen
dc.subjectCardiovascular Diseases/etiology/metabolismen
dc.subjectDiabetes Mellitus, Type 2/etiology/metabolismen
dc.subjectHumansen
dc.subjectLife Styleen
dc.subjectMetabolic Syndrome X/*complications/physiopathology/therapyen
dc.subjectObesity/complicationsen
dc.subjectRisk Factorsen
dc.subjectVascular Diseases/*complicationsen
dc.titleMetabolic syndrome and Alzheimer's disease: a link to a vascular hypothesis?en
heal.typejournalArticle-
heal.type.enJournal articleen
heal.type.elΆρθρο Περιοδικούel
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/18622365-
heal.languageen-
heal.accesscampus-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.publicationDate2008-
heal.abstractCurrent evidence from epidemiological, neuroimaging, pathological, pharmacotherapeutic, and clinical studies indicate an association of Alzheimer's disease with risk factors of vascular atherosclerotic disease either in isolation or in aggregate. "Metabolic syndrome" (MetS) is the name for a clustering of risk factors for cardiovascular disease and type 2 diabetes that are of metabolic origin. These include central obesity, elevated plasma glucose, high blood pressure, atherogenic dyslipidemia, a prothrombotic state, and a proinflammatory state. In this article, we provide an overview of the relevant literature with regard to the relationship of Alzheimer's disease with MetS. Accumulating evidence suggests a "vascular hypothesis" to be related to the pathology of Alzheimer's disease. In the light of this evidence, clinician may consider lifestyle interventions toward an early and effective cardiovascular risk-factor management to reduce the cardiometabolic and the cognitive decline risk, while further research of other preventive strategies may be warranted.en
heal.journalNameCNS Spectren
heal.journalTypepeer-reviewed-
heal.fullTextAvailabilityTRUE-
Appears in Collections:Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά) - ΙΑΤ

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