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  5. Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά) - ΙΑΤ
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Please use this identifier to cite or link to this item: https://olympias.lib.uoi.gr/jspui/handle/123456789/19992
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dc.contributor.authorKonstandi, M.en
dc.contributor.authorPappas, P.en
dc.contributor.authorJohnson, E.en
dc.contributor.authorLecklin, A.en
dc.contributor.authorKarageorgou, M.en
dc.contributor.authorMarselos, M.en
dc.date.accessioned2015-11-24T19:04:11Z-
dc.date.available2015-11-24T19:04:11Z-
dc.identifier.issn1043-6618-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/19992-
dc.rightsDefault Licence-
dc.subjectAnimalsen
dc.subjectCentral Nervous System/physiologyen
dc.subjectEstradiol/blooden
dc.subjectEstrus/drug effectsen
dc.subjectFemaleen
dc.subjectLitter Size/drug effectsen
dc.subjectMaleen
dc.subjectMethylcholanthrene/*toxicityen
dc.subjectOrgan Size/drug effectsen
dc.subjectProgesterone/blooden
dc.subjectRatsen
dc.subjectRats, Wistaren
dc.subjectReproduction/*drug effectsen
dc.subjectTestis/anatomy & histology/drug effectsen
dc.subjectTestosterone/blooden
dc.titleModification of reproductive function in the rat by 3-methylcholanthreneen
heal.typejournalArticle-
heal.type.enJournal articleen
heal.type.elΆρθρο Περιοδικούel
heal.identifier.primary10.1006/phrs.1996.0123-
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/9175578-
heal.identifier.secondaryhttp://ac.els-cdn.com/S1043661896901231/1-s2.0-S1043661896901231-main.pdf?_tid=e821415680fc8bc0d383aa6a7525217c&acdnat=1333002433_f294d56ef46f69200d2637ab8ffc5df3-
heal.languageen-
heal.accesscampus-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.publicationDate1997-
heal.abstractRepeated exposure of adult female Wistar rats to 3-methylcholanthrene (MC) (25 mg kg(-1) b.w., i.p., 2xwk, 1 mo) was associated with a significant increase in estrus cycle length. In addition, an increased frequency of females with constant diestrus and abnormal cycles was observed. Young females which had been exposed to MC prepubertally or whose parents had been treated with MC before and during mating also demonstrated cycle prolongation and an increased incidence of constant diestrus and abnormal cycles. These changes in female reproductive function were not associated with measurable changes in plasma sex hormone levels. In contrast, MC exposure in adult males was associated with significant reductions in circulating plasma testosterone levels. The present data also suggest that the offspring of parents who had been exposed repeatedly to MC before and during mating are also affected. Although the central nervous system in offspring of MC-treated parents appeared to be intact, their oral body temperature was significantly lower.en
heal.journalNamePharmacol Resen
heal.journalTypepeer-reviewed-
heal.fullTextAvailabilityTRUE-
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