Please use this identifier to cite or link to this item:
https://olympias.lib.uoi.gr/jspui/handle/123456789/19963Full metadata record
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Ntais, C. | en |
| dc.contributor.author | Polycarpou, A. | en |
| dc.contributor.author | Tsatsoulis, A. | en |
| dc.date.accessioned | 2015-11-24T19:04:03Z | - |
| dc.date.available | 2015-11-24T19:04:03Z | - |
| dc.identifier.issn | 0804-4643 | - |
| dc.identifier.uri | https://olympias.lib.uoi.gr/jspui/handle/123456789/19963 | - |
| dc.rights | Default Licence | - |
| dc.subject | 3-Hydroxysteroid Dehydrogenases/genetics | en |
| dc.subject | 3-Oxo-5-alpha-Steroid 4-Dehydrogenase/genetics | en |
| dc.subject | Androgens/*genetics | en |
| dc.subject | Aromatase/genetics | en |
| dc.subject | Continental Population Groups/genetics | en |
| dc.subject | Genetic Markers/genetics | en |
| dc.subject | Humans | en |
| dc.subject | Male | en |
| dc.subject | Polymorphism, Genetic/*genetics | en |
| dc.subject | Prostatic Neoplasms/ethnology/*genetics | en |
| dc.subject | Receptors, Androgen/genetics | en |
| dc.subject | Steroid 17-alpha-Hydroxylase/genetics | en |
| dc.subject | Tumor Markers, Biological/*genetics | en |
| dc.title | Molecular epidemiology of prostate cancer: androgens and polymorphisms in androgen-related genes | en |
| heal.type | journalArticle | - |
| heal.type.en | Journal article | en |
| heal.type.el | Άρθρο Περιοδικού | el |
| heal.identifier.secondary | http://www.ncbi.nlm.nih.gov/pubmed/14640986 | - |
| heal.identifier.secondary | http://www.eje-online.org/content/149/6/469.full.pdf | - |
| heal.language | en | - |
| heal.access | campus | - |
| heal.recordProvider | Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής | el |
| heal.publicationDate | 2003 | - |
| heal.abstract | In most western countries prostate cancer is the most commonly diagnosed non-skin cancer in men. Despite its high morbidity and mortality the etiology of prostate cancer remains obscure. The involvement of androgens has been examined extensively in prostate carcinogenesis but the results of most epidemiological studies remain inconclusive. This review focuses on current perspectives of androgen levels and polymorphisms in androgen-related genes. Racial differences in genetic polymorphisms that have a role in the biosynthesis and metabolism of androgens may partly account for racial differences in prostate cancer risk. Reasons are also given for inconsistent results in molecular epidemiological studies and insights and directions for future research are discussed. The development of a polygenic model for prostate cancer, incorporating multiple loci from the individual genes, may maximize the chance of identifying individuals with high-risk genotypes, resulting in better preventive, diagnostic, and therapeutic strategies. | en |
| heal.journalName | European Journal of Endocrinology | en |
| heal.journalType | peer-reviewed | - |
| heal.fullTextAvailability | TRUE | - |
| Appears in Collections: | Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά) - ΙΑΤ | |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| Ntais-2003-Molecular epidemiolo.pdf | 118.86 kB | Adobe PDF | View/Open Request a copy |
This item is licensed under a Creative Commons License
