Please use this identifier to cite or link to this item: https://olympias.lib.uoi.gr/jspui/handle/123456789/19872
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dc.contributor.authorFlorentin, M.en
dc.contributor.authorLiberopoulos, E. N.en
dc.contributor.authorWierzbicki, A. S.en
dc.contributor.authorMikhailidis, D. P.en
dc.date.accessioned2015-11-24T19:03:08Z-
dc.date.available2015-11-24T19:03:08Z-
dc.identifier.issn1531-7080-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/19872-
dc.rightsDefault Licence-
dc.subjectAnti-Infective Agents/metabolismen
dc.subjectAnti-Inflammatory Agents/metabolismen
dc.subjectAntioxidants/metabolismen
dc.subjectAtherosclerosis/*metabolismen
dc.subjectEndothelium, Vascular/metabolismen
dc.subjectFibrinolytic Agents/metabolismen
dc.subjectHumansen
dc.subjectKidney/metabolismen
dc.subjectLipoproteins, HDL/chemistry/*metabolismen
dc.subjectMolecular Structureen
dc.titleMultiple actions of high-density lipoproteinen
heal.typejournalArticle-
heal.type.enJournal articleen
heal.type.elΆρθρο Περιοδικούel
heal.identifier.primary10.1097/HCO.0b013e3283043806-
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/18520722-
heal.languageen-
heal.accesscampus-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.publicationDate2008-
heal.abstractPURPOSE OF REVIEW: The most accepted property of high-density lipoprotein is reverse cholesterol transport. However, other beneficial actions may contribute to the antiatherogenic role of high-density lipoprotein. This review addresses the action of high-density lipoprotein beyond reverse cholesterol transport. RECENT FINDINGS: High-density lipoprotein cholesterol levels are inversely associated with coronary heart disease and other forms of vascular disease. Apart from transferring excess cholesterol to the liver, high-density lipoprotein exhibits favorable effects on oxidation, inflammation, thrombosis and endothelial function. Some of these actions are at least in part attributed to high-density lipoprotein-associated enzymes, such as paraoxonase and platelet-activating factor acetylhydrolase. However, high-density lipoprotein can become dysfunctional and proatherogenic under certain circumstances. SUMMARY: Current data suggest that high-density lipoprotein possesses various properties beyond reverse cholesterol transport. However, many issues on the exact role of high-density lipoprotein remain unknown. Future research is needed.en
heal.journalNameCurr Opin Cardiolen
heal.journalTypepeer-reviewed-
heal.fullTextAvailabilityTRUE-
Appears in Collections:Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά) - ΙΑΤ

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