Please use this identifier to cite or link to this item: https://olympias.lib.uoi.gr/jspui/handle/123456789/19729
Full metadata record
DC FieldValueLanguage
dc.contributor.authorCosmi, E.en
dc.contributor.authorMari, G.en
dc.contributor.authorDelle Chiaie, L.en
dc.contributor.authorDetti, L.en
dc.contributor.authorAkiyama, M.en
dc.contributor.authorMurphy, J.en
dc.contributor.authorStefos, T.en
dc.contributor.authorFerguson, J. E., 2nden
dc.contributor.authorHunter, D.en
dc.contributor.authorHsu, C. D.en
dc.contributor.authorAbuhamad, A.en
dc.contributor.authorBahado-Singh, R.en
dc.date.accessioned2015-11-24T19:01:50Z-
dc.date.available2015-11-24T19:01:50Z-
dc.identifier.issn0002-9378-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/19729-
dc.rightsDefault Licence-
dc.subjectAnemia/diagnosis/*ultrasonography/*virologyen
dc.subjectBlood Flow Velocityen
dc.subjectCordocentesisen
dc.subjectFemaleen
dc.subjectFetal Diseases/diagnosis/*ultrasonography/*virologyen
dc.subjectFetus/physiologyen
dc.subjectGestational Ageen
dc.subjectHumansen
dc.subjectHydrops Fetalis/ultrasonographyen
dc.subjectMiddle Cerebral Artery/embryology/ultrasonographyen
dc.subjectParvoviridae Infections/*complicationsen
dc.subject*Parvovirus B19, Humanen
dc.subjectPregnancyen
dc.subject*Pregnancy Complications, Infectiousen
dc.subjectSystoleen
dc.subject*Ultrasonography, Doppleren
dc.titleNoninvasive diagnosis by Doppler ultrasonography of fetal anemia resulting from parvovirus infectionen
heal.typejournalArticle-
heal.type.enJournal articleen
heal.type.elΆρθρο Περιοδικούel
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/12439522-
heal.languageen-
heal.accesscampus-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.publicationDate2002-
heal.abstractOBJECTIVE: The purpose of this study was to evaluate the feasibility of the middle cerebral artery peak systolic velocity for the detection of fetal anemia in pregnancies that are complicated by parvovirus B19 infection. STUDY DESIGN: Doppler measurements of the middle cerebral artery peak systolic velocity were performed weekly in 32 fetuses at risk for anemia because of maternal parvovirus infection documented by the presence of serum immunoglobulin M antibody. The values of the middle cerebral artery peak systolic velocity and hemoglobin were expressed as multiples of the median. These values were plotted on reference ranges that had been established previously. A cordocentesis was performed either because of fetal ascites or when the middle cerebral artery peak systolic velocity values suggested anemia (middle cerebral artery peak systolic velocity, >1.50 multiples of the median). RESULTS: Gestational age at study entry ranged from 15.1 to 37 weeks. There were 17 fetuses with middle cerebral artery peak systolic velocity of >1.50 MoM (group 1). Sixteen cordocenteses were performed in these fetuses. All 16 fetuses were anemic (15 severely and 1 mildly). Thirteen fetuses had signs of hydrops (12 with severe and 1 with mild anemia). Group 2 included 15 fetuses with the middle cerebral artery peak systolic velocity values <1.50 MoM. Two cordocenteses were performed. One fetus was mildly anemic; the second fetus was not anemic. The remaining 13 fetuses of this group did not have any complications and were not anemic at birth. The sensitivity of the middle cerebral artery peak systolic velocity (>1.50 MoM) for the prediction of anemia because of parvovirus infection was 94.1%; the specificity was 93.3 %; the positive and negative predictive values were 94.1% and 93.3%, respectively. CONCLUSION: Fetal anemia caused by parvovirus infection can be detected noninvasively by Doppler ultrasonography on the basis of an increase in the peak velocity of systolic blood flow in the middle cerebral artery.en
heal.journalNameAm J Obstet Gynecolen
heal.journalTypepeer-reviewed-
heal.fullTextAvailabilityTRUE-
Appears in Collections:Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά) - ΙΑΤ

Files in This Item:
There are no files associated with this item.


This item is licensed under a Creative Commons License Creative Commons