Please use this identifier to cite or link to this item: https://olympias.lib.uoi.gr/jspui/handle/123456789/19680
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dc.contributor.authorKavantzas, N.en
dc.contributor.authorAgapitos, E.en
dc.contributor.authorLazaris, A. C.en
dc.contributor.authorPavlopoulos, P. M.en
dc.contributor.authorSofikitis, N.en
dc.contributor.authorDavaris, P.en
dc.date.accessioned2015-11-24T19:01:22Z-
dc.date.available2015-11-24T19:01:22Z-
dc.identifier.issn0392-9078-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/19680-
dc.rightsDefault Licence-
dc.subjectAdenocarcinoma/genetics/*pathology/surgeryen
dc.subjectBiopsyen
dc.subjectCell Nucleolus/*pathologyen
dc.subjectCell Nucleus/*pathologyen
dc.subjectDNA, Neoplasm/*analysisen
dc.subjectHumansen
dc.subjectImage Processing, Computer-Assisteden
dc.subjectMaleen
dc.subjectParaffin Embeddingen
dc.subject*Ploidiesen
dc.subjectProstatic Neoplasms/genetics/*pathology/surgeryen
dc.titleNuclear/Nucleolar morphometry and DNA image cytometry as a combined diagnostic tool in pathology of prostatic carcinomaen
heal.typejournalArticle-
heal.type.enJournal articleen
heal.type.elΆρθρο Περιοδικούel
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/11876548-
heal.languageen-
heal.accesscampus-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.publicationDate2001-
heal.abstractParaffin tissue sections from 50 patients with prostate adenocarcinoma were used to study nuclear and nucleolar morphometric features by image analysis. The results were compared to DNA ploidy and Gleason grade. In the examined histological samples nuclear and nucleolar areas were positively interrelated. It was also noticed that the higher the percentage of nucleolated nuclei, the bigger the nuclear and nucleolar areas. The morphometric characteristics did not differ significantly among the four grades of the examined specimens. In well-differentiated carcinomas the DNA index was lower than in the rest at a statistically significant level. Hypodiploid carcinomas were found to possess significantly bigger nuclear areas than any other DNA index group. Morphonuclear evidence of anaplasia and DNA aneuploidy may be used as diagnostic tools in prostate cancer in addition to Gleason grade.en
heal.journalNameJ Exp Clin Cancer Resen
heal.journalTypepeer-reviewed-
heal.fullTextAvailabilityTRUE-
Appears in Collections:Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά) - ΙΑΤ

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