Please use this identifier to cite or link to this item: https://olympias.lib.uoi.gr/jspui/handle/123456789/19671
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dc.contributor.authorDerdemezis, C. S.en
dc.contributor.authorVoulgari, P. V.en
dc.contributor.authorDrosos, A. A.en
dc.contributor.authorKiortsis, D. N.en
dc.date.accessioned2015-11-24T19:01:18Z-
dc.date.available2015-11-24T19:01:18Z-
dc.identifier.issn0392-856X-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/19671-
dc.rightsDefault Licence-
dc.subjectadipokinesen
dc.subjectrheumatoid arthritisen
dc.subjectleptinen
dc.subjectadiponectinen
dc.subjectvisfatinen
dc.subjectresistinen
dc.subjectnecrosis-factor-alphaen
dc.subjectproliferator-activated-receptoren
dc.subjectbody-mass indexen
dc.subjectsystemic-lupus-erythematosusen
dc.subjectcollagen-induced arthritisen
dc.subjectcolony-enhancing factoren
dc.subjectinflammatory-bowel-diseaseen
dc.subjectserum leptin levelsen
dc.subjectfibroblast-like synoviocytesen
dc.subjectdirect adipotropic actionsen
dc.titleObesity, adipose tissue and rheumatoid arthritis: coincidence or more complex relationship?en
heal.typejournalArticle-
heal.type.enJournal articleen
heal.type.elΆρθρο Περιοδικούel
heal.identifier.secondary<Go to ISI>://000295351900018-
heal.languageen-
heal.accesscampus-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.publicationDate2011-
heal.abstractIn the last two decades we have witnessed a boost in scientific interest and knowledge of adipose tissue biology to such an extent that it was promoted to an active endocrine organ. Adipose tissue is not just related to body weight and appetite regulation. It is also implicated in obesity, a low-grade inflammatory state, as well as inflammatory conditions including rheumatoid arthritis (RA), an autoimmune disease where anti- and pro-inflammatory cytokine balance is critical. All major adipose derived products, simply termed adipokines, like leptin, adiponectin, visfatin and resistin, reportedly participate in inflammation and immunity. In this review we explore in depth the relationship between adipose tissue and RA, with focus on possible mechanisms, beyond observations about circulating or synovial levels, and special reference to future perspectives and clinical implications.en
heal.journalNameClin Exp Rheumatolen
heal.journalTypepeer-reviewed-
heal.fullTextAvailabilityTRUE-
Appears in Collections:Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά) - ΙΑΤ

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