Please use this identifier to cite or link to this item: https://olympias.lib.uoi.gr/jspui/handle/123456789/19437
Full metadata record
DC FieldValueLanguage
dc.contributor.authorGiannopoulos, S.en
dc.contributor.authorKosmidou, M.en
dc.contributor.authorSarmas, I.en
dc.contributor.authorMarkoula, S.en
dc.contributor.authorPelidou, S. H.en
dc.contributor.authorLagos, G.en
dc.contributor.authorKyritsis, A. P.en
dc.date.accessioned2015-11-24T18:59:54Z-
dc.date.available2015-11-24T18:59:54Z-
dc.identifier.issn0749-8047-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/19437-
dc.rightsDefault Licence-
dc.subjectAdulten
dc.subjectAmines/*therapeutic useen
dc.subjectAnalgesics/*therapeutic useen
dc.subjectAnticonvulsantsen
dc.subjectChi-Square Distributionen
dc.subjectCyclohexanecarboxylic Acids/*therapeutic useen
dc.subjectDiabetic Neuropathies/*drug therapy/*psychologyen
dc.subjectFemaleen
dc.subjectFollow-Up Studiesen
dc.subjectHumansen
dc.subjectMaleen
dc.subjectMiddle Ageden
dc.subjectPain Measurementen
dc.subject*Patient Complianceen
dc.subjectProspective Studiesen
dc.subjectSerotonin Uptake Inhibitors/*therapeutic useen
dc.subjectgamma-Aminobutyric Acid/*therapeutic useen
dc.titlePatient compliance with SSRIs and gabapentin in painful diabetic neuropathyen
heal.typejournalArticle-
heal.type.enJournal articleen
heal.type.elΆρθρο Περιοδικούel
heal.identifier.primary10.1097/AJP.0b013e31802fc14a-
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/17314587-
heal.languageen-
heal.accesscampus-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.publicationDate2007-
heal.abstractBACKGROUND: Anticonvulsants are widely used for treatment of painful diabetic neuropathy. Selective serotonin reuptake inhibitors (SSRIs) are not first-line drugs but are commonly prescribed medicines for chronic pain. The majority of patients are hesitant to use these drug groups, thus their compliance remains an issue. OBJECTIVE: To compare patient compliance and the effectiveness of 2 SSRIs (paroxetine or citalopram) and 1 anticonvulsant (gabapentin) in patients with painful diabetic neuropathy. METHODS: This was a 6 months prospective trial in 101 patients with painful diabetic neuropathy and minimum score of 2 on a pain intensity scale ranging of 0 to 4. Compliance was assessed with patient interviews and pill counts. Adverse events, early discontinuation or satisfaction with treatment were also evaluated. RESULTS: Patients receiving SSRIs reported greater satisfaction and fewer concerns of the side-effects with their treatment (P<0.05) compared with the patients taking gabapentin. There was statistically significant better mood in the SSRI group (P<0.05). Overall, 43.5% of those taking SSRIs noticed no effect on the pain control, 50% felt better, and 6.5% felt worse. Among the patients taking gabapentin, 51% felt better, 40.5% noticed no effect, and 8.5% felt worse. Finally, on the pill count, more patients on SSRIs (93.5%) than on gabapentin (82.9%) were taking over the 75% of their medication (P<0.05). CONCLUSIONS: The lack of negative effects on quality of life, the better compliance, and the comparable efficiency of SSRIs suggest that these drugs may be considered as alternative to gabapentin in painful diabetic neuropathy.en
heal.journalNameClin J Painen
heal.journalTypepeer-reviewed-
heal.fullTextAvailabilityTRUE-
Appears in Collections:Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά) - ΙΑΤ

Files in This Item:
There are no files associated with this item.


This item is licensed under a Creative Commons License Creative Commons