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  5. Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά) - ΙΑΤ
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Please use this identifier to cite or link to this item: https://olympias.lib.uoi.gr/jspui/handle/123456789/19403
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dc.contributor.authorBuller, C. E.en
dc.contributor.authorRankin, J. M.en
dc.contributor.authorCarere, R. G.en
dc.contributor.authorBuszman, P. E.en
dc.contributor.authorPfisterer, M. E.en
dc.contributor.authorDzavik, V.en
dc.contributor.authorThomas, B.en
dc.contributor.authorForman, S.en
dc.contributor.authorRuzyllo, W.en
dc.contributor.authorMancini, G. B.en
dc.contributor.authorMichalis, L. K.en
dc.contributor.authorAbreu, P. F.en
dc.contributor.authorLamas, G. A.en
dc.contributor.authorHochman, J. S.en
dc.date.accessioned2015-11-24T18:59:45Z-
dc.date.available2015-11-24T18:59:45Z-
dc.identifier.issn1097-6744-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/19403-
dc.rightsDefault Licence-
dc.subjectAgeden
dc.subject*Angioplasty, Balloon, Coronary/adverse effectsen
dc.subjectCardiovascular Agents/therapeutic useen
dc.subjectClinical Protocolsen
dc.subjectCohort Studiesen
dc.subjectCoronary Angiographyen
dc.subjectCoronary Occlusion/complications/radiography/*therapyen
dc.subjectFemaleen
dc.subjectHumansen
dc.subjectMaleen
dc.subjectMiddle Ageden
dc.subjectMyocardial Infarction/etiology/*therapyen
dc.subjectTreatment Outcomeen
dc.titlePercutaneous coronary intervention in the Occluded Artery Trial: procedural success, hazard, and outcomes over 5 yearsen
heal.typejournalArticle-
heal.type.enJournal articleen
heal.type.elΆρθρο Περιοδικούel
heal.identifier.primary10.1016/j.ahj.2009.05.035-
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/19699864-
heal.identifier.secondaryhttp://ac.els-cdn.com/S000287030900458X/1-s2.0-S000287030900458X-main.pdf?_tid=55629d3b17f872e7ddfd5b5fa0eaa3b6&acdnat=1333606583_4284fc11c1004c9e3e075897f1705a48-
heal.languageen-
heal.accesscampus-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.publicationDate2009-
heal.abstractBACKGROUND: The Occluded Artery Trial (OAT) was a 2,201-patient randomized clinical trial comparing routine stent-based percutaneous coronary intervention (PCI) versus optimal medical therapy alone in stable myocardial infarction (MI) survivors with persistent infarct-related artery occlusion identified day 3 to 28 post MI. Intent-to-treat analysis showed no difference between strategies with respect to the incidence of new class IV congestive heart failure, MI, or death. The influence of PCI failure, procedural hazard, and crossover on trial results has not been reported. METHODS: Study angiograms were analyzed and adjudicated centrally. Factors associated with PCI failure were examined. Time-to-event analysis using the OAT primary outcome was performed by PCI success status. Landmark analysis (up to and beyond 30 days) partitioned early hazard versus late outcome according to treatment received. RESULTS: Percutaneous coronary intervention was adjudicated successful in >87%. Percutaneous coronary intervention failure rates were similar in US and non-US sites, and did not significantly influence outcome at 60 months (hazard ratio for success vs fail 0.79, 99% CI 0.45-1.40, P = .29). Partitioning of early procedural hazard revealed no late benefit for PCI (hazard ratio for PCI success vs medical therapy alone 1.06, 99% CI 0.75-1.50, P = .66). CONCLUSIONS: Percutaneous coronary intervention failure and complication rates in the OAT were low. Neither PCI failure nor early procedural hazard substantively influenced the primary trial results.en
heal.journalNameAm Heart Jen
heal.journalTypepeer-reviewed-
heal.fullTextAvailabilityTRUE-
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