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https://olympias.lib.uoi.gr/jspui/handle/123456789/19272Full metadata record
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Argyropoulou, M. I. | en |
| dc.contributor.author | Kiortsis, D. N. | en |
| dc.contributor.author | Metafratzi, Z. | en |
| dc.contributor.author | Bitsis, S. | en |
| dc.contributor.author | Tsatoulis, A. | en |
| dc.contributor.author | Efremidis, S. C. | en |
| dc.date.accessioned | 2015-11-24T18:58:22Z | - |
| dc.date.available | 2015-11-24T18:58:22Z | - |
| dc.identifier.issn | 0028-3940 | - |
| dc.identifier.uri | https://olympias.lib.uoi.gr/jspui/handle/123456789/19272 | - |
| dc.rights | Default Licence | - |
| dc.subject | pituitary | en |
| dc.subject | magnetic resonance imaging | en |
| dc.subject | beta-thalassemia major | en |
| dc.subject | hypogonadotropic hypogonadism | en |
| dc.subject | hypogonadotropic hypogonadism | en |
| dc.subject | gonadotropin-secretion | en |
| dc.subject | precocious puberty | en |
| dc.subject | hormone | en |
| dc.subject | hemochromatosis | en |
| dc.title | Pituitary gland height evaluated by MR in patients with beta-thalassemia major: a marker of pituitary gland function | en |
| heal.type | journalArticle | - |
| heal.type.en | Journal article | en |
| heal.type.el | Άρθρο Περιοδικού | el |
| heal.identifier.secondary | <Go to ISI>://000172745200005 | - |
| heal.identifier.secondary | http://www.springerlink.com/content/et6827xkl83w1wmp/fulltext.pdf | - |
| heal.language | en | - |
| heal.access | campus | - |
| heal.recordProvider | Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής | el |
| heal.publicationDate | 2001 | - |
| heal.abstract | In transfusion-dependent beta -thalassemia major, increased iron deposition in the pituitary gland has a cytotoxic effect leading mainly to hypogonadotropic hypogonadism. Our purpose was to assess in these patients the height of the pituitary gland and to evaluate whether it represents a marker of pituitary gland function. In 29 patients with beta -thalassemia major and 35 age- and gender-matched controls the pituitary gland height was evaluated in a midline sagittal scan using a spin echo T1-weighted (500/20 TR/TE) sequence. In all patients, an extensive endocrine evaluation was performed, including measurements of spontaneous and stimulated levels of gonadotropins, thyroid hormones, growth hormone, insulinlike growth factor, and adrenal hormones. The pituitary gland height was lower in thalassemic patients with hypogonadotropic hypogonadism (n = 15) (mean 3.48; SD 0.46) than in the age- and gender-matched controls (mean 6.29; SD 0.77), (P < 0.001). No statistically significant difference was found between thalassemic patients without hormone dysfunction (n = 14) (mean 534; SD 1.52) and age- and gender-matched controls (mean 5.91; SD 1.06). We conclude that in thalassemic patients the pituitary gland height is an additional marker of pituitary gland function and might be useful in clinical management. | en |
| heal.journalName | Neuroradiology | en |
| heal.journalType | peer-reviewed | - |
| heal.fullTextAvailability | TRUE | - |
| Appears in Collections: | Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά) - ΙΑΤ | |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| Argyropoulou-2001-Pituitary gland heig.pdf | 49.17 kB | Adobe PDF | View/Open Request a copy |
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