Please use this identifier to cite or link to this item: https://olympias.lib.uoi.gr/jspui/handle/123456789/19079
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dc.contributor.authorPakos, E. E.en
dc.contributor.authorPitouli, E. J.en
dc.contributor.authorTsekeris, P. G.en
dc.contributor.authorPapathanasopoulou, V.en
dc.contributor.authorStafilas, K.en
dc.contributor.authorXenakis, T. H.en
dc.date.accessioned2015-11-24T18:56:42Z-
dc.date.available2015-11-24T18:56:42Z-
dc.identifier.issn0341-2695-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/19079-
dc.rightsDefault Licence-
dc.subjectAdulten
dc.subjectAgeden
dc.subjectAged, 80 and overen
dc.subjectAnti-Inflammatory Agents, Non-Steroidal/*therapeutic useen
dc.subject*Arthroplasty, Replacement, Hipen
dc.subjectChi-Square Distributionen
dc.subjectCombined Modality Therapyen
dc.subjectFemaleen
dc.subjectHumansen
dc.subjectIndomethacin/*therapeutic useen
dc.subjectMaleen
dc.subjectMiddle Ageden
dc.subjectOssification, Heterotopic/drug therapy/*prevention &en
dc.subjectcontrol/radiography/radiotherapyen
dc.subjectRadiotherapy Dosageen
dc.subjectTreatment Outcomeen
dc.titlePrevention of heterotopic ossification in high-risk patients with total hip arthroplasty: the experience of a combined therapeutic protocolen
heal.typejournalArticle-
heal.type.enJournal articleen
heal.type.elΆρθρο Περιοδικούel
heal.identifier.primary10.1007/s00264-005-0054-y-
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/16482442-
heal.identifier.secondaryhttp://www.springerlink.com/content/g26p445k08883588/fulltext.pdf-
heal.languageen-
heal.accesscampus-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.publicationDate2006-
heal.abstractThe combination of radiotherapy and indomethacin for the prevention of heterotopic ossification (HO) in high-risk patients undergoing total hip arthroplasty (THA) has not been reported. The aim of the present study was to present the experience of our department with this combined therapeutic protocol. Fifty-four patients who underwent THA received a single dose of 7 Gy of postoperative radiotherapy and 75 mg of indomethacin for 15 days. Patients were analyzed for clinical and radiographical evidence of HO development at 1 year postoperatively. The overall radiographical incidence of HO was 20.4% (95% CI 10.6-33.5%), while only 1 patient with clinically significant HO was seen. Patients with secondary arthritis due to congenital hip disease had a statistically significantly higher incidence of HO compared with those with osteoarthrosis. The clinical assessment with the Merle d'Aubigne score showed that patients with radiographic documentation of HO had a lower mean score compared with those with no evidence of HO. No treatment-related side effects were seen. Combined radiotherapy and indomethacin was effective in preventing heterotopic ossification after total hip arthroplasty. The evaluation of this efficacy compared with radiotherapy or NSAIDs alone should be the future target of larger randomized designs.en
heal.journalNameInt Orthopen
heal.journalTypepeer-reviewed-
heal.fullTextAvailabilityTRUE-
Appears in Collections:Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά) - ΙΑΤ

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