Please use this identifier to cite or link to this item: https://olympias.lib.uoi.gr/jspui/handle/123456789/19076
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dc.contributor.authorKappas, A. M.en
dc.contributor.authorBarsoum, G. H.en
dc.contributor.authorOrtiz, J. B.en
dc.contributor.authorKeighley, M. R.en
dc.date.accessioned2015-11-24T18:56:40Z-
dc.date.available2015-11-24T18:56:40Z-
dc.identifier.issn1102-4151-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/19076-
dc.rightsDefault Licence-
dc.subjectAnimalsen
dc.subjectFemaleen
dc.subjectHydrocortisone/*analogs & derivatives/therapeutic useen
dc.subjectPeritoneal Diseases/*prevention & controlen
dc.subjectPeritoneal Lavageen
dc.subjectPhosphatidylcholines/*therapeutic useen
dc.subjectPostoperative Complications/*prevention & controlen
dc.subjectRatsen
dc.subjectRats, Inbred Strainsen
dc.subjectSodium Chlorideen
dc.subjectTissue Adhesions/prevention & controlen
dc.subjectVerapamil/*therapeutic useen
dc.titlePrevention of peritoneal adhesions in rats with verapamil, hydrocortisone sodium succinate, and phosphatidylcholineen
heal.typejournalArticle-
heal.type.enJournal articleen
heal.type.elΆρθρο Περιοδικούel
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/1348638-
heal.languageen-
heal.accesscampus-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.publicationDate1992-
heal.abstractOBJECTIVE: To assess the effectiveness of verapamil, hydrocortisone sodium succinate, and phosphatidylcholine in the prevention of experimental adhesions. DESIGN: Randomized trial. MATERIAL: 80 rats. INTERVENTIONS: Laparotomy and intraperitoneal irrigation with saline 40 degrees C, then verapamil hydrochloride 1 mg/kg intravenously 15 min before, during, and after irrigation; or hydrocortisone sodium succinate 50 mg/kg intravenously half an hour before irrigation; or phosphatidylcholine 5.5 mg/kg orally eight days before and seven days after irrigation plus 0.5 mg/ml in the irrigation fluid; or no further intervention. MAIN OUTCOME MEASURES: Development of adhesions two weeks after irrigation, and completeness of wound healing. RESULTS: Adhesions developed in 13 of 19 control animals; 7 of 20 that were given verapamil; 6 of 20 that were given hydrocortisone; and 3 of 20 given phosphatidylcholine. CONCLUSION: Adhesions that developed in rats after laparotomy and intraperitoneal irrigation with saline at 40 degrees C can be significantly reduced by phosphatidylcholine.en
heal.journalNameEur J Surgen
heal.journalTypepeer-reviewed-
heal.fullTextAvailabilityTRUE-
Appears in Collections:Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά) - ΙΑΤ

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