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DC Field | Value | Language |
---|---|---|
dc.contributor.author | Papaxoinis, G. | en |
dc.contributor.author | Papageorgiou, S. | en |
dc.contributor.author | Rontogianni, D. | en |
dc.contributor.author | Kaloutsi, V. | en |
dc.contributor.author | Fountzilas, G. | en |
dc.contributor.author | Pavlidis, N. | en |
dc.contributor.author | Dimopoulos, M. | en |
dc.contributor.author | Tsatalas, C. | en |
dc.contributor.author | Xiros, N. | en |
dc.contributor.author | Economopoulos, T. | en |
dc.date.accessioned | 2015-11-24T18:56:34Z | - |
dc.date.available | 2015-11-24T18:56:34Z | - |
dc.identifier.issn | 1042-8194 | - |
dc.identifier.uri | https://olympias.lib.uoi.gr/jspui/handle/123456789/19061 | - |
dc.rights | Default Licence | - |
dc.subject | Adolescent | en |
dc.subject | Adult | en |
dc.subject | Aged | en |
dc.subject | Aged, 80 and over | en |
dc.subject | Disease-Free Survival | en |
dc.subject | Female | en |
dc.subject | Gastrointestinal Neoplasms/*diagnosis/*pathology/therapy | en |
dc.subject | Greece | en |
dc.subject | Humans | en |
dc.subject | Lymphoma, Non-Hodgkin/*diagnosis/*pathology/therapy | en |
dc.subject | Male | en |
dc.subject | Middle Aged | en |
dc.subject | Prognosis | en |
dc.subject | Time Factors | en |
dc.subject | Treatment Outcome | en |
dc.title | Primary gastrointestinal non-Hodgkin's lymphoma: a clinicopathologic study of 128 cases in Greece. A Hellenic Cooperative Oncology Group study (HeCOG) | en |
heal.type | journalArticle | - |
heal.type.en | Journal article | en |
heal.type.el | Άρθρο Περιοδικού | el |
heal.identifier.primary | 10.1080/10428190600709226 | - |
heal.identifier.secondary | http://www.ncbi.nlm.nih.gov/pubmed/17071488 | - |
heal.identifier.secondary | http://informahealthcare.com/doi/abs/10.1080/10428190600709226 | - |
heal.language | en | - |
heal.access | campus | - |
heal.recordProvider | Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής | el |
heal.publicationDate | 2006 | - |
heal.abstract | The aim of this retrospective study was to illustrate the clinicopathologic data and the treatment results in patients with primary gastrointestinal tract non-Hodgkin's lymphoma (GI NHL). Among 810 patients with NHL, 128 cases (15.8%) were diagnosed as primary GI tract NHL. There were 79 males and 49 females with median age of 62 years. The most common primary site was the stomach (68%). Overall, 67.2% of the patients were in stages I - II, and 32.8% in stages III - IV. Simultaneous involvement of the GI tract and other extranodal sites was observed in 26 patients (20%). Extranodal marginal zone B-cell lymphoma (MZBL) (i.e., low-grade lymphoma of mucosa-associated lymphoid tissue type) accounted for 48.4% of lymphomas. Aggressive lymphomas (diffuse large B-cell lymphoma [DLBL]) accounted for 44.5%. Eighty-three patients (67.5%) achieved complete response (CR), either by surgery (43/43 patients, 17 with DLBL and 25 with MZBL) or by primary chemotherapy (40/64 patients, 22 with DLBL and 17 with MZBL). Sixty-two patients remain in CR; 33/43 after surgical resection (13/17 with DLBL and 20/25 patients with MZBL), and 29/40 after only chemotherapy (18/22 with DLBL and 10/17 with MZBL). The major prognostic factor for outcome in the present study was the stage of the disease. Patients with localized lymphoma (stage I and II) had significantly longer DFS and OS (DFS and OS at 3-year: 83% and 87%, respectively) than patients with extended disease (stage III and IV) (DFS and OS at 3-year: 46% and 60%, respectively) (P < 0.0001). The International Prognostic Index (IPI) for patients with aggressive lymphomas was prognostic only for DFS (79% for low-risk patients [IPI score 0 - 1] vs 49% for higher risk groups [IPI score >1] at 3-year, P = 0.0131). | en |
heal.journalName | Leuk Lymphoma | en |
heal.journalType | peer-reviewed | - |
heal.fullTextAvailability | TRUE | - |
Appears in Collections: | Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά) - ΙΑΤ |
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