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Please use this identifier to cite or link to this item: https://olympias.lib.uoi.gr/jspui/handle/123456789/19055
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dc.contributor.authorGiapros, V. I.en
dc.contributor.authorPapaloukas, A. L.en
dc.contributor.authorChalla, A. S.en
dc.contributor.authorNikolopoulos, P. D.en
dc.contributor.authorTsampoulas, C. G.en
dc.contributor.authorAndronikou, S. K.en
dc.date.accessioned2015-11-24T18:56:32Z-
dc.date.available2015-11-24T18:56:32Z-
dc.identifier.issn0340-6199-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/19055-
dc.rightsDefault Licence-
dc.subjectAnimalsen
dc.subjectCalcium/urineen
dc.subjectCreatinine/*urineen
dc.subjectHumansen
dc.subject*Infant Formulaen
dc.subjectInfant, Newbornen
dc.subjectInfant, Prematureen
dc.subjectInfant, Premature, Diseases/*urineen
dc.subjectKidney Calculi/*urineen
dc.subjectMagnesium/urineen
dc.subjectMilken
dc.subjectOxalates/*urineen
dc.subject*Parenteral Nutrition, Totalen
dc.titleUrinary lithogenic and inhibitory factors in preterm neonates receiving either total parenteral nutrition or milk formulaen
heal.typejournalArticle-
heal.type.enJournal articleen
heal.type.elΆρθρο Περιοδικούel
heal.identifier.primary10.1007/s00431-003-1209-8-
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/12750999-
heal.identifier.secondaryhttp://www.springerlink.com/content/bp582lkhdbqr1jv8/fulltext.pdf-
heal.languageen-
heal.accesscampus-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.publicationDate2003-
heal.abstractThe aim of this study was to evaluate prospectively the influence of nutrition on certain factors which may inhibit or promote nephrocalcinosis in two groups of preterm infants, receiving total parenteral nutrition (TPN) and special preterm milk formula respectively, but not furosemide. A total of 37 preterm infants, 15 on TPN and 22 fed a special preterm formula were studied at the end of the 1st, 2nd and 3rd weeks of life, at which time serum and 8 h urine specimens were collected. High ratios of urinary calcium to urinary creatinine (UCa/cr), urinary oxalate to urinary creatinine (Uox/cr) and urinary calcium to urinary citrate (UCa/cit) indicates an increased risk for nephrocalcinosis while high urinary citrate to urinary creatinine (Ucit/cr) ratio indicates protection. Uox/cr increased significantly (P<0.05) in those infants fed preterm formula, from the end of 2nd week of life and was two-fold higher than in the TPN group of preterm infants (P<0.01). Ucit/cr was higher throughout the study period in the formula fed than in the TPN preterm infants. UCa/cit was five-fold higher (P<0.01) in the TPN group, by the end of the 3rd week. Urinary calcium and magnesium was similar in both groups during the study period. Two of the infants studied (5.4%), one from each group, developed nephrocalcinosis.CONCLUSION: In preterm neonates on total parenteral nutrition, urinary oxalate -to-creatinine ratio (a potent lithogenic factor) was lower and urinary citrate -to-creatinine ratio (a lithoprotective factor) also lower than in formula fed neonates. The type of feeding (total parenteral nutrition or special preterm milk formula) seems to affect urinary oxalate and citrate but not calcium and magnesium in non-furosemide treated preterm infants during the first 3 weeks of life.en
heal.journalNameEur J Pediatren
heal.journalTypepeer-reviewed-
heal.fullTextAvailabilityTRUE-
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