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https://olympias.lib.uoi.gr/jspui/handle/123456789/18947Full metadata record
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Evagelidou, E. N. | en |
| dc.contributor.author | Giapros, V. I. | en |
| dc.contributor.author | Challa, A. S. | en |
| dc.contributor.author | Cholevas, V. K. | en |
| dc.contributor.author | Vartholomatos, G. A. | en |
| dc.contributor.author | Siomou, E. C. | en |
| dc.contributor.author | Kolaitis, N. I. | en |
| dc.contributor.author | Bairaktari, E. T. | en |
| dc.contributor.author | Andronikou, S. K. | en |
| dc.date.accessioned | 2015-11-24T18:55:53Z | - |
| dc.date.available | 2015-11-24T18:55:53Z | - |
| dc.identifier.issn | 1935-5548 | - |
| dc.identifier.uri | https://olympias.lib.uoi.gr/jspui/handle/123456789/18947 | - |
| dc.rights | Default Licence | - |
| dc.subject | Birth Weight/*physiology | en |
| dc.subject | Cardiovascular Diseases/*epidemiology | en |
| dc.subject | Child | en |
| dc.subject | Enzyme-Linked Immunosorbent Assay | en |
| dc.subject | Female | en |
| dc.subject | Gestational Age | en |
| dc.subject | Humans | en |
| dc.subject | Male | en |
| dc.subject | Metabolic Syndrome X/*epidemiology | en |
| dc.subject | Regression Analysis | en |
| dc.subject | Thrombosis/*epidemiology | en |
| dc.title | Prothrombotic state, cardiovascular, and metabolic syndrome risk factors in prepubertal children born large for gestational age | en |
| heal.type | journalArticle | - |
| heal.type.en | Journal article | en |
| heal.type.el | Άρθρο Περιοδικού | el |
| heal.identifier.primary | 10.2337/dc10-1190 | - |
| heal.identifier.secondary | http://www.ncbi.nlm.nih.gov/pubmed/20724652 | - |
| heal.identifier.secondary | http://care.diabetesjournals.org/content/33/11/2468.full.pdf | - |
| heal.language | en | - |
| heal.access | campus | - |
| heal.recordProvider | Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής | el |
| heal.publicationDate | 2010 | - |
| heal.abstract | OBJECTIVE: To evaluate metabolic syndrome and cardiovascular disease risk factors in prepubertal children born large for gestational age (LGA) to nondiabetic, nonobese mothers. RESEARCH DESIGN AND METHODS: At 6-7 years of age, the comparison of various factors was made between 31 LGA and 34 appropriate-for-gestational-age (AGA) children: fibrinogen, antithrombin III, protein C and S, fasting insulin, glucose, homeostasis assessment model of insulin resistance (HOMA-IR) index, adiponectin, leptin, visfatin, IGF-1, IGF-binding protein (IGFBP)-1, IGFBP-3, lipids, and the genetic factors V Leiden G1691A mutation, prothrombin 20210A/G polymorphism, and mutation in the enzyme 5,10-methylenetetrahydrofolate-reductase gene (MTHFR-C677T). RESULTS: LGA children had higher levels of leptin (P<0.01), fasting insulin (P<0.01), and HOMA-IR (P<0.01), but lower IGFBP-3 (P=0.0001), fibrinogen (P=0.0001), and lipoprotein(a) (P<0.001) than AGA children. Significantly more LGA children were homozygous for the MTHFR-C677T mutation (P=0.0016). CONCLUSIONS: Being born LGA to nondiabetic, nonobese mothers is associated with diverse effects on cardiometabolic risk factors at prepuberty. | en |
| heal.journalName | Diabetes Care | en |
| heal.journalType | peer-reviewed | - |
| heal.fullTextAvailability | TRUE | - |
| Appears in Collections: | Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά) - ΙΑΤ | |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| Evagelidou-2010-Prothrombotic state.pdf | 66.87 kB | Adobe PDF | View/Open Request a copy |
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