Please use this identifier to cite or link to this item: https://olympias.lib.uoi.gr/jspui/handle/123456789/18943
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dc.contributor.authorNikas, S. N.en
dc.contributor.authorVoulgari, P. V.en
dc.contributor.authorDrosos, A. A.en
dc.date.accessioned2015-11-24T18:55:52Z-
dc.date.available2015-11-24T18:55:52Z-
dc.identifier.issn0770-3198-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/18943-
dc.rightsDefault Licence-
dc.subjectAntibodies, Monoclonal/*adverse effectsen
dc.subjectAntibodies, Monoclonal, Humanizeden
dc.subjectAntirheumatic Agents/*adverse effectsen
dc.subjectArthritis, Rheumatoid/*drug therapyen
dc.subjectFemaleen
dc.subjectHumansen
dc.subjectMiddle Ageden
dc.subjectUrticaria/*chemically induceden
dc.titleUrticaria and angiedema-like skin reactions in a patient treated with adalimumaben
heal.typejournalArticle-
heal.type.enJournal articleen
heal.type.elΆρθρο Περιοδικούel
heal.identifier.primary10.1007/s10067-005-0197-7-
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/16421645-
heal.identifier.secondaryhttp://www.springerlink.com/content/p4kx2254886309xv/fulltext.pdf-
heal.languageen-
heal.accesscampus-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.publicationDate2007-
heal.abstractSpecific inhibition of the cytokine tumor necrosis factor alpha has resulted in significant clinical and laboratory improvement of patients with chronic inflammatory diseases of Th1 phenotype. Etanercept is a recombinant fusion protein of two p75 soluble receptors, while infliximab is a chimeric monoclonal antibody. Both have been considered to be immunogenic and cause various immune-mediated skin reactions. On the other hand, adalimumab, a human monoclonal antibody, was expected to cause little or no immune-mediated skin reactions. Herein, we report a patient with rheumatoid arthritis treated with adalimumab, who after the seventh injection, developed angiedema affecting the lips and face, as well as an urticaria-like skin reaction affecting the trunk. These reactions were followed by hypotension. The patient was treated appropriately and after 2 h, the rashes and the edema disappeared and the patient gradually recovered completely. Adalimumab was discontinued.en
heal.journalNameClin Rheumatolen
heal.journalTypepeer-reviewed-
heal.fullTextAvailabilityTRUE-
Appears in Collections:Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά) - ΙΑΤ

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