1. Repository of OAI
  2. ΑΠΟΘΕΤΗΡΙΟ "ΟΛΥΜΠΙΑΣ"
  3. Σχολή Επιστημών Υγείας
  4. Τμήμα Ιατρικής
  5. Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά) - ΙΑΤ
Ελληνικά   English  
Please use this identifier to cite or link to this item: https://olympias.lib.uoi.gr/jspui/handle/123456789/18935
Full metadata record
DC FieldValueLanguage
dc.contributor.authorTzika, A. A.en
dc.contributor.authorZurakowski, D.en
dc.contributor.authorPoussaint, T. Y.en
dc.contributor.authorGoumnerova, L.en
dc.contributor.authorAstrakas, L. G.en
dc.contributor.authorBarnes, P. D.en
dc.contributor.authorAnthony, D. C.en
dc.contributor.authorBillett, A. L.en
dc.contributor.authorTarbell, N. J.en
dc.contributor.authorScott, R. M.en
dc.contributor.authorBlack, P. M.en
dc.date.accessioned2015-11-24T18:55:49Z-
dc.date.available2015-11-24T18:55:49Z-
dc.identifier.issn0028-3940-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/18935-
dc.rightsDefault Licence-
dc.subjectAdolescenten
dc.subjectAdulten
dc.subjectBrain/metabolism/pathologyen
dc.subjectBrain Chemistryen
dc.subjectBrain Neoplasms/metabolism/*pathology/therapyen
dc.subjectChilden
dc.subjectChild, Preschoolen
dc.subjectFemaleen
dc.subjectHumansen
dc.subjectInfanten
dc.subjectLogistic Modelsen
dc.subjectMagnetic Resonance Imagingen
dc.subjectMagnetic Resonance Spectroscopy/*diagnostic useen
dc.subjectMaleen
dc.titleProton magnetic spectroscopic imaging of the child's brain: the response of tumors to treatmenten
heal.typejournalArticle-
heal.type.enJournal articleen
heal.type.elΆρθρο Περιοδικούel
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/11326567-
heal.languageen-
heal.accesscampus-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.publicationDate2001-
heal.abstractOur aim was to determine and/or predict response to treatment of brain tumors in children using proton magnetic resonance spectro-scopic imaging (MRSI). We studied 24 patients aged 10 months to 24 years, using MRI and point-resolved spectroscopy (PRESS; TR 2000 TE 65 ms) with volume preselection and phase-encoding in two dimensions on a 1.5 T imager. Multiple logistic regression was used to establish independent predictors of active tumor growth. Biologically vital cell metabolites, such as N-acetyl aspartate and choline-containing compounds (Cho), were significantly different between tumor and control tissues (P < 0.001). The eight brain tumors which responded to radiation or chemotherapy, exhibited lower Cho (P = 0.05), higher total creatine (tCr) (P = 0.02) and lower lactate and lipid (L) (P = 0.04) than 16 tumors which were not treated (except by surgery) or did not respond to treatment. The only significant independent predictor of active tumor growth was tCr (P < 0.01). We suggest that tCr is useful in assessing response of brain tumors to treatment.en
heal.journalNameNeuroradiologyen
heal.journalTypepeer-reviewed-
heal.fullTextAvailabilityTRUE-
Appears in Collections:Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά) - ΙΑΤ

Show simple item record
Files in This Item:
There are no files associated with this item.
Show simple item record  


This item is licensed under a Creative Commons License Creative Commons