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| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Dueymes, M. | en |
| dc.contributor.author | Barrier, J. | en |
| dc.contributor.author | Besancenot, J. F. | en |
| dc.contributor.author | Cledes, J. | en |
| dc.contributor.author | Conri, C. | en |
| dc.contributor.author | Dien, G. | en |
| dc.contributor.author | Drosos, A. A. | en |
| dc.contributor.author | Dueymes, J. M. | en |
| dc.contributor.author | Galanaud, P. | en |
| dc.contributor.author | Grobois, B. | en |
| dc.contributor.author | et al., | en |
| dc.date.accessioned | 2015-11-24T18:54:30Z | - |
| dc.date.available | 2015-11-24T18:54:30Z | - |
| dc.identifier.issn | 1018-2438 | - |
| dc.identifier.uri | https://olympias.lib.uoi.gr/jspui/handle/123456789/18691 | - |
| dc.rights | Default Licence | - |
| dc.subject | Adolescent | en |
| dc.subject | Adult | en |
| dc.subject | Aged | en |
| dc.subject | Aged, 80 and over | en |
| dc.subject | Antibodies, Antinuclear/*blood | en |
| dc.subject | DNA/*immunology | en |
| dc.subject | Female | en |
| dc.subject | Humans | en |
| dc.subject | Immunoglobulin Isotypes/classification | en |
| dc.subject | Interleukin-4/*blood | en |
| dc.subject | Lupus Erythematosus, Systemic/blood/*immunology | en |
| dc.subject | Male | en |
| dc.subject | Middle Aged | en |
| dc.title | Relationship of interleukin-4 to isotypic distribution of anti-double-stranded DNA antibodies in systemic lupus erythematosus | en |
| heal.type | journalArticle | - |
| heal.type.en | Journal article | en |
| heal.type.el | Άρθρο Περιοδικού | el |
| heal.identifier.secondary | http://www.ncbi.nlm.nih.gov/pubmed/8353462 | - |
| heal.identifier.secondary | http://content.karger.com/ProdukteDB/produkte.asp?doi=10.1159/000236484 | - |
| heal.language | en | - |
| heal.access | campus | - |
| heal.recordProvider | Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής | el |
| heal.publicationDate | 1993 | - |
| heal.abstract | IgG subclasses of anti-double-stranded DNA antibodies were determined in 182 patients with systemic lupus erythematosus. All isotypes were detected, but IgG1 and IgG3 were predominant (62 and 51% of the cases, respectively). An average of 64 +/- 27% was IgG1, 16 +/- 22% IgG2, 16 +/- 19% IgG3 and 4 +/- 10% IgG4. The rank order or frequency was IgG1, IgG3, IgG2 and IgG4 in patients with musculoskeletal involvement; IgG1, IgG2, IgG3 and IgG4 in those with renal complications; IgG3, IgG1, IgG2 and IgG4 in those with cutaneous involvement; and IgG1, IgG3, IgG2 and IgG4 in those with hematological manifestations. Interleukin-4 (IL-4) was detectable in 17 of 36 selected patients, as opposed to 1 of 40 normal controls. The percentage of the total autoantibody contributed by IgG1 was significantly higher (p < 0.03) in these patients than in the remainder with undetectable levels of IL-4. | en |
| heal.journalName | Int Arch Allergy Immunol | en |
| heal.journalType | peer-reviewed | - |
| heal.fullTextAvailability | TRUE | - |
| Appears in Collections: | Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά) - ΙΑΤ | |
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