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  5. Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά) - ΙΑΤ
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Please use this identifier to cite or link to this item: https://olympias.lib.uoi.gr/jspui/handle/123456789/18675
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dc.contributor.authorGiapros, V. I.en
dc.contributor.authorAndronikou, S. K.en
dc.contributor.authorCholevas, V. I.en
dc.contributor.authorPapadopoulou, Z. L.en
dc.date.accessioned2015-11-24T18:54:21Z-
dc.date.available2015-11-24T18:54:21Z-
dc.identifier.issn0931-041X-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/18675-
dc.rightsDefault Licence-
dc.subjectAmikacin/adverse effects/therapeutic useen
dc.subjectAminoglycosides/*adverse effectsen
dc.subjectAnti-Bacterial Agents/*adverse effects/therapeutic useen
dc.subjectGentamicins/adverse effects/therapeutic useen
dc.subjectHumansen
dc.subjectInfant, Newbornen
dc.subjectInfant, Prematureen
dc.subjectInfant, Premature, Diseases/*drug therapyen
dc.subjectInfection/*drug therapyen
dc.subjectKidney/*drug effects/growth & developmenten
dc.subjectKidney Function Testsen
dc.subjectNetilmicin/adverse effects/therapeutic useen
dc.subjectPhosphorus/metabolismen
dc.subjectPotassium/metabolismen
dc.subjectSodium/metabolismen
dc.subjectUric Acid/metabolismen
dc.titleRenal function and effect of aminoglycoside therapy during the first ten days of lifeen
heal.typejournalArticle-
heal.type.enJournal articleen
heal.type.elΆρθρο Περιοδικούel
heal.identifier.primary10.1007/s00467-002-1001-4-
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/12488990-
heal.identifier.secondaryhttp://www.springerlink.com/content/yv21qgancdgnyk6m/fulltext.pdf-
heal.languageen-
heal.accesscampus-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.publicationDate2003-
heal.abstractThe effect of aminoglycoside administration on kidney functional maturation was evaluated in groups of 30 preterm and 30 fullterm infants who were treated for 7 days because of suspected infection. One of three different aminoglycosides was administered to each subgroup of ten preterm and ten fullterm infants. Changes in tubular function in groups of ten preterm and ten fullterm infants who were not given antibiotics were also compared. The mean gestational age for preterm infants from 32.5 to 33.6 weeks and for fullterm infants between 39.2 and 39.5 weeks. The renal tubular function was assessed by examining the fractional excretion of sodium (FENa), potassium (FEK), phosphorus (FEP), magnesium (FEMg) and uric acid (FEUA) as well as by the urinary excretion of calcium as the calcium/creatinine (UCa/UCr) ratio. Gentamicin affected the normal plasma creatinine (PCr) decline in both treated groups (fullterm and preterm). Disturbances in FENa and UCa/UCr were more pronounced in treated preterm than in fullterm infants especially after netilmicin and gentamicin administration. FEMg was significantly affected in preterm infants treated with gentamicin. The findings of this study indicate that the effect of aminoglycosides on tubular function is dependent upon kidney maturity and the type of the aminoglycoside used for therapy.en
heal.journalNamePediatr Nephrolen
heal.journalTypepeer-reviewed-
heal.fullTextAvailabilityTRUE-
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