Please use this identifier to cite or link to this item:
https://olympias.lib.uoi.gr/jspui/handle/123456789/18593Full metadata record
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Dedepsidis, E. | en |
| dc.contributor.author | Kyriakopoulou, Z. | en |
| dc.contributor.author | Pliaka, V. | en |
| dc.contributor.author | Kottaridi, C. | en |
| dc.contributor.author | Bolanaki, E. | en |
| dc.contributor.author | Levidiotou-Stefanou, S. | en |
| dc.contributor.author | Komiotis, D. | en |
| dc.contributor.author | Markoulatos, P. | en |
| dc.date.accessioned | 2015-11-24T18:53:41Z | - |
| dc.date.available | 2015-11-24T18:53:41Z | - |
| dc.identifier.issn | 0099-2240 | - |
| dc.identifier.uri | https://olympias.lib.uoi.gr/jspui/handle/123456789/18593 | - |
| dc.rights | Default Licence | - |
| dc.subject | Capsid Proteins/chemistry/*genetics | en |
| dc.subject | Greece/epidemiology | en |
| dc.subject | Humans | en |
| dc.subject | Poliomyelitis/*epidemiology/prevention & control/virology | en |
| dc.subject | Poliovirus/classification/genetics/*isolation & purification | en |
| dc.subject | *Poliovirus Vaccine, Oral | en |
| dc.subject | Recombination, Genetic | en |
| dc.subject | Retrospective Studies | en |
| dc.subject | Sequence Analysis, DNA | en |
| dc.subject | Sewage/*virology | en |
| dc.title | Retrospective characterization of a vaccine-derived poliovirus type 1 isolate from sewage in Greece | en |
| heal.type | journalArticle | - |
| heal.type.en | Journal article | en |
| heal.type.el | Άρθρο Περιοδικού | el |
| heal.identifier.primary | 10.1128/AEM.00535-07 | - |
| heal.identifier.secondary | http://www.ncbi.nlm.nih.gov/pubmed/17827314 | - |
| heal.identifier.secondary | http://aem.asm.org/content/73/21/6697.full.pdf | - |
| heal.language | en | - |
| heal.access | campus | - |
| heal.recordProvider | Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής | el |
| heal.publicationDate | 2007 | - |
| heal.abstract | Retrospective molecular and phenotypic characterization of a vaccine-derived poliovirus (VDPV) type 1 isolate (7/b/97) isolated from sewage in Athens, Greece, in 1997 is reported. VP1 sequencing of this isolate revealed 1.87% divergence from the VP1 region of reference strain Sabin 1, while further genomic characterization of isolate 7/b/97 revealed a recombination event in the nonstructural part of the genome between a vaccine strain and a nonvaccine strain probably belonging to Enterovirus species C. Amino acid substitutions commonly found in previous studies were identified in the capsid coding region of the isolate, while most of the attenuation and temperature sensitivity determinants were reverted. The ultimate source of isolate 7/b/97 is unknown. The recovery of such a highly divergent derivative of a vaccine strain emphasizes the need for urgent implementation of environmental surveillance as a supportive procedure in the polio surveillance system even in countries with high rates of OPV coverage in order to prevent cases or even outbreaks of poliomyelitis that otherwise would be inevitable. | en |
| heal.journalName | Appl Environ Microbiol | en |
| heal.journalType | peer-reviewed | - |
| heal.fullTextAvailability | TRUE | - |
| Appears in Collections: | Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά) - ΙΑΤ | |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| Dedepsidis-2007-Retrospective charac.pdf | 324.52 kB | Adobe PDF | View/Open Request a copy |
This item is licensed under a Creative Commons License
