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  5. Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά) - ΙΑΤ
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Please use this identifier to cite or link to this item: https://olympias.lib.uoi.gr/jspui/handle/123456789/18552
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dc.contributor.authorTektonidou, M. G.en
dc.contributor.authorIoannidis, J. P.en
dc.contributor.authorMoyssakis, I.en
dc.contributor.authorBoki, K. A.en
dc.contributor.authorVassiliou, V.en
dc.contributor.authorVlachoyiannopoulos, P. G.en
dc.contributor.authorKyriakidis, M. K.en
dc.contributor.authorMoutsopoulos, H. M.en
dc.date.accessioned2015-11-24T18:53:23Z-
dc.date.available2015-11-24T18:53:23Z-
dc.identifier.issn0003-4967-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/18552-
dc.rightsDefault Licence-
dc.subjectAdulten
dc.subjectAntibodies, Anticardiolipin/*blooden
dc.subjectAntiphospholipid Syndrome/*complications/immunologyen
dc.subjectBiological Markers/blooden
dc.subjectCross-Sectional Studiesen
dc.subjectDiastole/physiologyen
dc.subjectEchocardiography, Doppler, Coloren
dc.subjectEchocardiography, Doppler, Pulseden
dc.subjectFemaleen
dc.subjectHumansen
dc.subjectImmunoglobulin G/blooden
dc.subjectLupus Erythematosus, Systemic/complicationsen
dc.subjectMaleen
dc.subjectRegression Analysisen
dc.subjectVentricular Dysfunction, Right/*etiology/immunology/ultrasonographyen
dc.titleRight ventricular diastolic dysfunction in patients with anticardiolipin antibodies and antiphospholipid syndromeen
heal.typejournalArticle-
heal.type.enJournal articleen
heal.type.elΆρθρο Περιοδικούel
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/11114281-
heal.identifier.secondaryhttp://ard.bmj.com/content/60/1/43.full.pdf-
heal.languageen-
heal.accesscampus-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.publicationDate2001-
heal.abstractOBJECTIVE: To evaluate the prevalence of diastolic dysfunction in patients with anticardiolipin antibodies (aCL) and to examine whether the antiphospholipid syndrome (APS) is associated with diastolic dysfunction independently of valvular abnormalities and systolic dysfunction. METHODS: Pulsed, continuous, colour Doppler echocardiography was performed in 179 subjects, of whom 15 were excluded from the analysis because of systolic dysfunction or severe valvular disease. The remaining 164 subjects included 29 patients with primary APS, 26 patients with secondary APS (APS in the presence of systemic lupus erythematosus (SLE)), and 30 patients with SLE and aCL but without APS; 43 patients with SLE without aCL and 36 normal volunteers served as control groups. RESULTS: The groups compared differed significantly in all measures of right ventricular function. There was a gradation of increasing diastolic function impairment as manifested by prolonged deceleration time (DT) and isovolumic relaxation time (IVRT) across the groups of patients with SLE without aCL, SLE with aCL, secondary APS, and primary APS. Differences in left ventricular diastolic function measures were less prominent. In regression analysis, DT increased by 19.6 ms (p=0.002) in the presence of primary APS and by 20.1 ms (p=0.038) in the presence of pulmonary hypertension. The titre of IgG aCL was the strongest predictor of a prolonged IVRT. CONCLUSION: Diastolic dysfunction, in particular of the right ventricle-that is, independent of valvular disease and systolic dysfunction, is a prominent feature of APS and may be related to the pathogenesis of the syndrome.en
heal.journalNameAnn Rheum Disen
heal.journalTypepeer-reviewed-
heal.fullTextAvailabilityTRUE-
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