Please use this identifier to cite or link to this item:
https://olympias.lib.uoi.gr/jspui/handle/123456789/18394Full metadata record
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Rosen, J. F. | en |
| dc.contributor.author | Markowitz, M. E. | en |
| dc.contributor.author | Bijur, P. E. | en |
| dc.contributor.author | Jenks, S. T. | en |
| dc.contributor.author | Wielopolski, L. | en |
| dc.contributor.author | Kalef-Ezra, J. A. | en |
| dc.contributor.author | Slatkin, D. N. | en |
| dc.date.accessioned | 2015-11-24T18:52:23Z | - |
| dc.date.available | 2015-11-24T18:52:23Z | - |
| dc.identifier.issn | 0091-6765 | - |
| dc.identifier.uri | https://olympias.lib.uoi.gr/jspui/handle/123456789/18394 | - |
| dc.rights | Default Licence | - |
| dc.subject | Bone and Bones/*chemistry | en |
| dc.subject | *Chelation Therapy | en |
| dc.subject | Child, Preschool | en |
| dc.subject | Edetic Acid/*diagnostic use | en |
| dc.subject | Humans | en |
| dc.subject | Lead/*analysis | en |
| dc.subject | Lead Poisoning/blood/*therapy | en |
| dc.subject | Longitudinal Studies | en |
| dc.subject | *Spectrometry, X-Ray Emission | en |
| dc.subject | Tibia/chemistry | en |
| dc.title | Sequential measurements of bone lead content by L X-ray fluorescence in CaNa2EDTA-treated lead-toxic children | en |
| heal.type | journalArticle | - |
| heal.type.en | Journal article | en |
| heal.type.el | Άρθρο Περιοδικού | el |
| heal.identifier.secondary | http://www.ncbi.nlm.nih.gov/pubmed/1773798 | - |
| heal.language | en | - |
| heal.access | campus | - |
| heal.recordProvider | Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής | el |
| heal.publicationDate | 1991 | - |
| heal.abstract | With the development of L X-ray fluorescence (LXRF) to measure cortical bone lead directly, safely, rapidly, and noninvasively, the present study was undertaken to a) evaluate LXRF as a possible replacement for the CaNa2EDTA test; b) quantify lead in tibial cortical bones of mildly to moderately lead-toxic children before treatment; and c) quantify lead in tibial cortical bones of lead-toxic children sequentially following one to two courses of chelation therapy. The clinical research design was based upon a longitudinal assessment of 59 untreated lead-toxic children. At enrollment, if the blood lead (PbB) was 25 to 55 micrograms/dL and the erythrocyte protoporphyrin (EP) concentration was greater than or equal to 35 micrograms/dL, LXRF measurement of tibial bone lead was carried out. One day later, each child underwent a CaNa2EDTA provocative test. If this test was positive, lead-toxic children were admitted to the hospital for 5 days of CaNa2EDTA therapy. These tests were repeated 6 weeks and 6 months after enrollment. Abatement of lead paint hazards was achieved in most apartments by the time of initial hospital discharge. The LXRF instrument consists of a low energy X-ray generator with a silver anode, a lithium-doped silicon detector, a polarizer of incident photons, and a multichannel X-ray analyzer. Partially polarized photons are directed at the subcutaneous, medial mid-tibial cortical bone. The LXRF spectrum, measured 90 degrees from the incident beam, reveals a peak in the 10.5 KeV region, which represents the lead L alpha line.(ABSTRACT TRUNCATED AT 250 WORDS) | en |
| heal.journalName | Environ Health Perspect | en |
| heal.journalType | peer-reviewed | - |
| heal.fullTextAvailability | TRUE | - |
| Appears in Collections: | Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά) - ΙΑΤ | |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| Kalef-1991-sequential measurements of.pdf | 1.19 MB | Adobe PDF | View/Open |
This item is licensed under a Creative Commons License
