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dc.contributor.authorBourantas, K. L.en
dc.contributor.authorHatzimichael, E. C.en
dc.contributor.authorMakis, A. C.en
dc.contributor.authorChaidos, A.en
dc.contributor.authorKapsali, E. D.en
dc.contributor.authorTsiara, S.en
dc.contributor.authorMavridis, A.en
dc.date.accessioned2015-11-24T18:52:12Z-
dc.date.available2015-11-24T18:52:12Z-
dc.identifier.issn0902-4441-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/18369-
dc.rightsDefault Licence-
dc.subjectAgeden
dc.subjectDisease Progressionen
dc.subjectFemaleen
dc.subjectHumansen
dc.subjectImmunoenzyme Techniquesen
dc.subjectInterleukins/*analysisen
dc.subjectMaleen
dc.subjectMiddle Ageden
dc.subjectMyeloproliferative Disorders/*blooden
dc.subjectTumor Markers, Biologicalen
dc.subjectTumor Necrosis Factor-alpha/*analysisen
dc.subjectbeta 2-Microglobulin/*analysisen
dc.titleSerum beta-2-microglobulin, TNF-alpha and interleukins in myeloproliferative disordersen
heal.typejournalArticle-
heal.type.enJournal articleen
heal.type.elΆρθρο Περιοδικούel
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/10414450-
heal.identifier.secondaryhttp://onlinelibrary.wiley.com/store/10.1111/j.1600-0609.1999.tb01845.x/asset/j.1600-0609.1999.tb01845.x.pdf?v=1&t=h0uocodl&s=d7ae427fd8349f5f31d9c635bb8dd1a2f5f42feb-
heal.languageen-
heal.accesscampus-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.publicationDate1999-
heal.abstractWhereas beta-2-microglobulin (beta2M) has mainly been used as a prognostic factor in patients with lymphoproliferative disorders, some studies have reported the value of beta2M in myeloproliferative disorders (MPD). In order to investigate a potential role in the pathogenesis of MPD and to find a possible value as indicators in monitoring the course of the disease, we measured beta2M, TNF-alpha, IL-1alpha, IL-1beta, IL-2, sIL-2R, IL-6 and IL-10 in 55 patients with MPD, at diagnosis and during the course of the disease. In progressive disease and particularly when transformation to acute leukemia occurred, high levels of beta2M, IL-2 and sIL-2R were found in all patients; the elevation was progressive, which suggests a potential prognostic usefulness in the individual patient.en
heal.journalNameEur J Haematolen
heal.journalTypepeer-reviewed-
heal.fullTextAvailabilityTRUE-
Appears in Collections:Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά) - ΙΑΤ

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