Please use this identifier to cite or link to this item:
https://olympias.lib.uoi.gr/jspui/handle/123456789/18340Full metadata record
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Milionis, H. J. | en |
| dc.contributor.author | Kalantzi, K. J. | en |
| dc.contributor.author | Goudevenos, J. A. | en |
| dc.contributor.author | Seferiadis, K. | en |
| dc.contributor.author | Mikhailidis, D. P. | en |
| dc.contributor.author | Elisaf, M. S. | en |
| dc.date.accessioned | 2015-11-24T18:52:00Z | - |
| dc.date.available | 2015-11-24T18:52:00Z | - |
| dc.identifier.issn | 0954-6820 | - |
| dc.identifier.uri | https://olympias.lib.uoi.gr/jspui/handle/123456789/18340 | - |
| dc.rights | Default Licence | - |
| dc.subject | Aged | en |
| dc.subject | Body Mass Index | en |
| dc.subject | Brain Ischemia/blood | en |
| dc.subject | Case-Control Studies | en |
| dc.subject | Female | en |
| dc.subject | Humans | en |
| dc.subject | Hypertension/blood/complications | en |
| dc.subject | Lipids/blood | en |
| dc.subject | Male | en |
| dc.subject | Metabolic Syndrome X/blood/complications | en |
| dc.subject | Risk Factors | en |
| dc.subject | Sex Factors | en |
| dc.subject | Stroke/*blood/etiology | en |
| dc.subject | Uric Acid/*blood | en |
| dc.title | Serum uric acid levels and risk for acute ischaemic non-embolic stroke in elderly subjects | en |
| heal.type | journalArticle | - |
| heal.type.en | Journal article | en |
| heal.type.el | Άρθρο Περιοδικού | el |
| heal.identifier.primary | 10.1111/j.1365-2796.2005.01565.x | - |
| heal.identifier.secondary | http://www.ncbi.nlm.nih.gov/pubmed/16238679 | - |
| heal.identifier.secondary | http://onlinelibrary.wiley.com/store/10.1111/j.1365-2796.2005.01565.x/asset/j.1365-2796.2005.01565.x.pdf?v=1&t=h0lzzqmy&s=b321b8c4f7ef4e9f0314848b7522f9833b06eebc | - |
| heal.language | en | - |
| heal.access | campus | - |
| heal.recordProvider | Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής | el |
| heal.publicationDate | 2005 | - |
| heal.abstract | BACKGROUND: Elevated serum uric acid (SUA) levels have been proposed as an independent risk factor for cardiovascular (CV) morbidity and mortality. Recent evidence suggests that treatments with a hypouricaemic action have a favourable effect on CV event prevention. OBJECTIVES: The association between SUA and acute ischaemic/non-embolic stroke was assessed in a population-based case-control study in the prefecture of Ioannina, Epirus, Greece. SUBJECTS AND METHODS: A total of 163 patients aged older than 70 years (88 men and 75 women) admitted due to a first-ever-in-a-lifetime acute ischaemic/non-embolic stroke and 166 volunteers (87 men and 79 women) without a history of CV disease were included. The association between SUA and stroke was determined by multivariate logistic regression modelling after adjusting for potential confounding factors. RESULTS: Stroke patients showed higher concentrations of SUA compared with controls (333.1+/-101.1 micromol L(-1) vs. 285.5+/-83.3 micromol L(-1); P<0.001). In univariate analysis elevated SUA levels were associated with increased risk for ischaemic stroke [odds ratio (OR) 1.42, 95% confidence interval (CI) 1.21-1.64, P<0.0001]. Compared to patients with SUA levels in the lowest quintile, those within the highest quintile had a 2.8-time increase in the odds of suffering an ischaemic stroke (OR 2.81, 95% CI 1.67-4.73, P<0.001). This association was strong even after controlling for gender, age, body mass index, the presence of hypertension and diabetes mellitus, drug treatment and lipids (OR 2.90, 95% CI 1.59-5.30, P=0.001). CONCLUSION: Elevated SUA is associated with an increased risk for acute ischaemic/non-embolic stroke in a strictly defined population of elderly individuals independently of concurrent metabolic derangements. This association may need to be considered when treating the elderly. | en |
| heal.journalName | J Intern Med | en |
| heal.journalType | peer-reviewed | - |
| heal.fullTextAvailability | TRUE | - |
| Appears in Collections: | Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά) - ΙΑΤ | |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| Milionis-2005-Serum uric acid leve.pdf | 89.25 kB | Adobe PDF | View/Open Request a copy |
This item is licensed under a Creative Commons License
