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| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Pavlidis, N. | en |
| dc.contributor.author | Nicolaides, C. | en |
| dc.contributor.author | Bairaktari, E. | en |
| dc.contributor.author | Kalef-Ezra, J. | en |
| dc.contributor.author | Athanassiadis, A. | en |
| dc.contributor.author | Seferiadis, C. | en |
| dc.contributor.author | Fountzilas, G. | en |
| dc.date.accessioned | 2015-11-24T18:51:05Z | - |
| dc.date.available | 2015-11-24T18:51:05Z | - |
| dc.identifier.issn | 0393-6155 | - |
| dc.identifier.uri | https://olympias.lib.uoi.gr/jspui/handle/123456789/18197 | - |
| dc.rights | Default Licence | - |
| dc.subject | Adult | en |
| dc.subject | Age Factors | en |
| dc.subject | Aged | en |
| dc.subject | CA-19-9 Antigen/blood | en |
| dc.subject | Carcinoembryonic Antigen/blood | en |
| dc.subject | Colorectal Neoplasms/immunology/mortality/*pathology/therapy | en |
| dc.subject | Female | en |
| dc.subject | Humans | en |
| dc.subject | Lymphatic Metastasis | en |
| dc.subject | Male | en |
| dc.subject | Middle Aged | en |
| dc.subject | Neoplasm Metastasis | en |
| dc.subject | Predictive Value of Tests | en |
| dc.subject | Prognosis | en |
| dc.subject | Receptors, Interleukin-2/*analysis | en |
| dc.subject | Reference Values | en |
| dc.subject | Sex Factors | en |
| dc.subject | Survival Analysis | en |
| dc.subject | Time Factors | en |
| dc.subject | Tumor Markers, Biological/*analysis/blood | en |
| dc.title | Soluble interleukin-2 receptors in patients with advanced colorectal carcinoma | en |
| heal.type | journalArticle | - |
| heal.type.en | Journal article | en |
| heal.type.el | Άρθρο Περιοδικού | el |
| heal.identifier.secondary | http://www.ncbi.nlm.nih.gov/pubmed/8740635 | - |
| heal.language | en | - |
| heal.access | campus | - |
| heal.recordProvider | Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής | el |
| heal.publicationDate | 1996 | - |
| heal.abstract | The levels of soluble interleukin-2 receptors (sIL-2R) were measured in the serum of 52 patients with advanced colorectal carcinoma and compared to CEA and CA 19-9 levels. Twenty-five normal, age and sex-matched individuals served as controls. Seventy-five per cent of the patients had increased mean serum levels of sIL-2R (1539 +/- 155 U/ml), while normal controls had mean levels of 555 +/- 31 U/ml (p < 0.001). The relationship with hepatic or lymph nodal metastases showed no statistically significant difference (p = 0.34 and p = 0.47, respectively). Serum sIL-2R levels showed a linear correlation with CEA (p < 0.05). Patients with lower pretreatment sIL-2R levels (less than 1.200 U/ml) had a longer survival than patients with higher initial levels (more than 1.200 U/ml) (p = 0.0049). In conclusion, the present work shows that the serum levels of sIL-2R: a) are elevated in patients with advanced colorectal cancer, b) have no relationship with the type of metastases, c) correlate with serum CEA and d) have a prognostic value for survival. | en |
| heal.journalName | Int J Biol Markers | en |
| heal.journalType | peer-reviewed | - |
| heal.fullTextAvailability | TRUE | - |
| Appears in Collections: | Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά) - ΙΑΤ | |
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