Please use this identifier to cite or link to this item: https://olympias.lib.uoi.gr/jspui/handle/123456789/18187
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dc.contributor.authorIoannidis, J. P.en
dc.date.accessioned2015-11-24T18:50:58Z-
dc.date.available2015-11-24T18:50:58Z-
dc.identifier.issn1936-9719-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/18187-
dc.rightsDefault Licence-
dc.subjectHumansen
dc.subject*Randomized Controlled Trials as Topicen
dc.subject*Research Designen
dc.subjectSample Sizeen
dc.subjectSelection Biasen
dc.titleSome main problems eroding the credibility and relevance of randomized trialsen
heal.typejournalArticle-
heal.type.enJournal articleen
heal.type.elΆρθρο Περιοδικούel
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/18537784-
heal.languageen-
heal.accesscampus-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.publicationDate2008-
heal.abstractRandomized trials are an excellent research design with major advantages. However, randomized trials are not immune to biases, and inferences from them may be sometimes flawed or irrelevant. The present review addresses, in brief, some of the major threats to the credibility and relevance of the results of clinical trials: power problems, biases affecting internal validity (poor design, conduct, and analysis), biases affecting the total randomized evidence on a specific topic (publication bias and selective outcome and analysis reporting bias), lack of relevance, poor generalizability, and biases in the interpretation of the results.en
heal.journalNameBull NYU Hosp Jt Disen
heal.journalTypepeer-reviewed-
heal.fullTextAvailabilityTRUE-
Appears in Collections:Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά) - ΙΑΤ

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