Please use this identifier to cite or link to this item: https://olympias.lib.uoi.gr/jspui/handle/123456789/18148
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dc.contributor.authorHatzimichael, E.en
dc.contributor.authorBenetatos, L.en
dc.contributor.authorStebbing, J.en
dc.contributor.authorKapsali, E.en
dc.contributor.authorPanayiotopoulou, S.en
dc.contributor.authorBourantas, K. L.en
dc.date.accessioned2015-11-24T18:50:47Z-
dc.date.available2015-11-24T18:50:47Z-
dc.identifier.issn0141-9854-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/18148-
dc.rightsDefault Licence-
dc.subjectAgeden
dc.subjectAnemia/etiologyen
dc.subjectFemaleen
dc.subjectGranulocyte Colony-Stimulating Factor/*adverse effects/therapeutic useen
dc.subjectHumansen
dc.subjectMultiple Myeloma/complications/*drug therapyen
dc.subjectRecombinant Proteinsen
dc.subjectRupture, Spontaneous/etiology/surgeryen
dc.subjectSplenic Rupture/blood/*etiology/surgeryen
dc.titleSpontaneous splenic haematoma in a multiple myeloma patient receiving pegfilgrastim supporten
heal.typejournalArticle-
heal.type.enJournal articleen
heal.type.elΆρθρο Περιοδικούel
heal.identifier.primary10.1111/j.1365-2257.2006.00819.x-
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/17105496-
heal.identifier.secondaryhttp://onlinelibrary.wiley.com/store/10.1111/j.1365-2257.2006.00819.x/asset/j.1365-2257.2006.00819.x.pdf?v=1&t=h2boq3so&s=5982923b9482bd73529e0b584d65ae85ebcd7796-
heal.languageen-
heal.accesscampus-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.publicationDate2006-
heal.abstractGrowth factors are a significant advance in the supportive care of patients with cancer with a wide range of indications. Frequent side effects of G-CSF include bone pain, headache, fatigue and nausea. We report a case of subcapsular splenic haematoma following pegfilgrastim administration in a 65-year old patient with multiple myeloma. Proposed mechanisms accounting for splenic enlargement include extramedullary haemopoiesis, intrasplenic infiltration by mature and immature myeloid cells and intrasplenic stem cell homing and proliferation. The risk of spontaneous splenic rupture is difficult to quantify. Physicians should be aware of this life-threatening condition and early diagnosis can be difficult since anemia and splenomegaly are common findings in haematologic patients.en
heal.journalNameClin Lab Haematolen
heal.journalTypepeer-reviewed-
heal.fullTextAvailabilityTRUE-
Appears in Collections:Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά) - ΙΑΤ

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