Please use this identifier to cite or link to this item: https://olympias.lib.uoi.gr/jspui/handle/123456789/18113
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dc.contributor.authorO'Neil-Callahan, K.en
dc.contributor.authorKatsimaglis, G.en
dc.contributor.authorTepper, M. R.en
dc.contributor.authorRyan, J.en
dc.contributor.authorMosby, C.en
dc.contributor.authorIoannidis, J. P.en
dc.contributor.authorDanias, P. G.en
dc.date.accessioned2015-11-24T18:50:37Z-
dc.date.available2015-11-24T18:50:37Z-
dc.identifier.issn0735-1097-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/18113-
dc.rightsDefault Licence-
dc.subjectAcute Diseaseen
dc.subjectAgeden
dc.subjectFemaleen
dc.subjectHeart Failure/etiology/mortality/*prevention & controlen
dc.subjectHumansen
dc.subjectHydroxymethylglutaryl-CoA Reductase Inhibitors/*therapeutic useen
dc.subjectMaleen
dc.subjectMiddle Ageden
dc.subjectMyocardial Infarction/etiology/mortality/*prevention & controlen
dc.subjectOdds Ratioen
dc.subjectRetrospective Studiesen
dc.subjectTachycardia, Ventricular/etiology/mortality/*prevention & controlen
dc.subjectTreatment Outcomeen
dc.subjectVascular Surgical Procedures/*adverse effectsen
dc.titleStatins decrease perioperative cardiac complications in patients undergoing noncardiac vascular surgery: the Statins for Risk Reduction in Surgery (StaRRS) studyen
heal.typejournalArticle-
heal.type.enJournal articleen
heal.type.elΆρθρο Περιοδικούel
heal.identifier.primary10.1016/j.jacc.2004.10.048-
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/15680709-
heal.identifier.secondaryhttp://ac.els-cdn.com/S0735109704021618/1-s2.0-S0735109704021618-main.pdf?_tid=e728b173c38332871b1f121b176fb7ac&acdnat=1333364363_967984f4d15148e38af5de4dfac300ad-
heal.languageen-
heal.accesscampus-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.publicationDate2005-
heal.abstractOBJECTIVES: We sought to assess whether statins may decrease cardiac complications in patients undergoing noncardiac vascular surgery. BACKGROUND: Cardiovascular complications account for considerable morbidity in patients undergoing noncardiac surgery. Statins decrease cardiac morbidity and mortality in patients with coronary disease, and the beneficial treatment effect is seen early, before any measurable increase in coronary artery diameter. METHODS: A retrospective study recorded patient characteristics, past medical history, and admission medications on all patients undergoing carotid endarterectomy, aortic surgery, or lower extremity revascularization over a two-year period (January 1999 to December 2000) at a tertiary referral center. Recorded perioperative complication outcomes included death, myocardial infarction, ischemia, congestive heart failure, and ventricular tachyarrhythmias occurring during the index hospitalization. Univariate and multivariate logistic regressions identified predictors of perioperative cardiac complications and medications that might confer a protective effect. RESULTS: Complications occurred in 157 of 1,163 eligible hospitalizations and were significantly fewer in patients receiving statins (9.9%) than in those not receiving statins (16.5%, p = 0.001). The difference was mostly accounted by myocardial ischemia and congestive heart failure. After adjusting for other significant predictors of perioperative complications (age, gender, type of surgery, emergent surgery, left ventricular dysfunction, and diabetes mellitus), statins still conferred a highly significant protective effect (odds ratio 0.52, p = 0.001). The protective effect was similar across diverse patient subgroups and persisted after accounting for the likelihood of patients to have hypercholesterolemia by considering their propensity to use statins. CONCLUSIONS: Use of statins was highly protective against perioperative cardiac complications in patients undergoing vascular surgery in this retrospective study.en
heal.journalNameJ Am Coll Cardiolen
heal.journalTypepeer-reviewed-
heal.fullTextAvailabilityTRUE-
Appears in Collections:Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά) - ΙΑΤ

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