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  5. Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά) - ΙΑΤ
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Please use this identifier to cite or link to this item: https://olympias.lib.uoi.gr/jspui/handle/123456789/18109
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dc.contributor.authorAlbert, J. M.en
dc.contributor.authorIoannidis, J. P.en
dc.contributor.authorReichelderfer, P.en
dc.contributor.authorConway, B.en
dc.contributor.authorCoombs, R. W.en
dc.contributor.authorCrane, L.en
dc.contributor.authorDemasi, R.en
dc.contributor.authorDixon, D. O.en
dc.contributor.authorFlandre, P.en
dc.contributor.authorHughes, M. D.en
dc.contributor.authorKalish, L. A.en
dc.contributor.authorLarntz, K.en
dc.contributor.authorLin, D.en
dc.contributor.authorMarschner, I. C.en
dc.contributor.authorMunoz, A.en
dc.contributor.authorMurray, J.en
dc.contributor.authorNeaton, J.en
dc.contributor.authorPettinelli, C.en
dc.contributor.authorRida, W.en
dc.contributor.authorTaylor, J. M.en
dc.contributor.authorWelles, S. L.en
dc.date.accessioned2015-11-24T18:50:36Z-
dc.date.available2015-11-24T18:50:36Z-
dc.identifier.issn0277-6715-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/18109-
dc.rightsDefault Licence-
dc.subject*Biological Markersen
dc.subjectCD4 Lymphocyte Counten
dc.subjectDisease Progressionen
dc.subjectHIV/geneticsen
dc.subjectHIV Infections/*diagnosis/therapyen
dc.subjectHumansen
dc.subject*Models, Statisticalen
dc.subjectProportional Hazards Modelsen
dc.subjectRNA, Viral/analysisen
dc.subjectStatistics as Topicen
dc.subjectTreatment Outcomeen
dc.titleStatistical issues for HIV surrogate endpoints: point/counterpoint. An NIAID workshopen
heal.typejournalArticle-
heal.type.enJournal articleen
heal.type.elΆρθρο Περιοδικούel
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/9819838-
heal.languageen-
heal.accesscampus-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.publicationDate1998-
heal.abstractThis paper summarizes the proceedings of an NIAID-sponsored workshop on statistical issues for HIV surrogate endpoints. The workshop brought together statisticians and clinicians in an attempt to shed light on some unresolved issues in the use of HIV laboratory markers (such as HIV RNA and CD4+ cell counts) in the design and analysis of clinical studies and in patient management. Utilizing a debate format, the workshop explored a series of specific questions dealing with the relationship between markers and clinical endpoints, and the choice of endpoints and methods of analysis in clinical studies. This paper provides the position statements from the two debaters on each issue. Consensus conclusions, based on the presentations and discussion, are outlined. While not providing final answers, we hope that these discussions have helped clarify a number of issues, and will stimulate further consideration of some of the highlighted problems. These issues will be critical in the proper assessment and use of future therapies for HIV disease.en
heal.journalNameStat Meden
heal.journalTypepeer-reviewed-
heal.fullTextAvailabilityTRUE-
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