Please use this identifier to cite or link to this item: https://olympias.lib.uoi.gr/jspui/handle/123456789/17999
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dc.contributor.authorTsiouris, S.en
dc.contributor.authorSioka, C.en
dc.contributor.authorMarinarou, A.en
dc.contributor.authorAl-Bokharhli, J.en
dc.contributor.authorSionti, I.en
dc.contributor.authorFotopoulos, A.en
dc.date.accessioned2015-11-24T18:49:44Z-
dc.date.available2015-11-24T18:49:44Z-
dc.identifier.issn0973-7693-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/17999-
dc.rightsDefault Licence-
dc.subjectChild, Preschoolen
dc.subjectFemaleen
dc.subjectHumansen
dc.subjectMandelic Acids/therapeutic useen
dc.subjectMuscarinic Antagonists/therapeutic useen
dc.subjectRadioisotope Renographyen
dc.subjectRadiopharmaceuticals/diagnostic useen
dc.subjectTechnetium Tc 99m Dimercaptosuccinic Acid/diagnostic useen
dc.subjectTwins, Monozygoticen
dc.subjectUrodynamicsen
dc.subjectVesico-Ureteral Reflux/*diagnosis/drug therapyen
dc.titleVesicoureteric reflux deterioration in monozygotic twinsen
heal.typejournalArticle-
heal.type.enJournal articleen
heal.type.elΆρθρο Περιοδικούel
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/18376100-
heal.languageen-
heal.accesscampus-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.publicationDate2008-
heal.abstractPrimary vesicoureteric reflux (VUR) is the most common inherited structural urinary tract disorder, conforming closely to autosomal dominant transmission. A pair of monozygotic siblings is described exhibiting a remarkably parallel clinical course. VUR grade II was diagnosed in girl A during urinary tract infection at the age of 2 yr; screening of her asymptomatic sister (girl B) revealed the same. Renal cortical scintigraphy unveiled unilateral hypo-dysplasia in both the twins. Despite trimethoprime-sulfamethoxazole prophylaxis, infection recurred in girl A after 7 months, while girl B had a first episode 2 months later that prompted regimen switch to nitrofurantoin. Follow-up at the age of 4 depicted bilateral reflux deterioration; an urodynamics study that followed revealed functional bladder instability in both girls and the oral antispasmodic oxybutynin was initiated with good results. Evaluation for reflux should be prompt in infants with urinary infection. Patient siblings display a higher relative reflux risk, being highest in identical twins. Heredity issues, the impact of age and dysfunctional voiding in the clinical course, and the contribution of nuclear medicine in VUR management are discussed.en
heal.journalNameIndian J Pediatren
heal.journalTypepeer-reviewed-
heal.fullTextAvailabilityTRUE-
Appears in Collections:Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά) - ΙΑΤ

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