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https://olympias.lib.uoi.gr/jspui/handle/123456789/17578Full metadata record
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Sioka, C. | en |
| dc.contributor.author | Exarchopoulos, T. | en |
| dc.contributor.author | Tasiou, I. | en |
| dc.contributor.author | Tzima, E. | en |
| dc.contributor.author | Fotou, N. | en |
| dc.contributor.author | Capizzello, A. | en |
| dc.contributor.author | Ragos, V. | en |
| dc.contributor.author | Tsekeris, P. | en |
| dc.contributor.author | Fotopoulos, A. | en |
| dc.date.accessioned | 2015-11-24T18:40:11Z | - |
| dc.date.available | 2015-11-24T18:40:11Z | - |
| dc.identifier.issn | 1748-717X | - |
| dc.identifier.uri | https://olympias.lib.uoi.gr/jspui/handle/123456789/17578 | - |
| dc.rights | Default Licence | - |
| dc.subject | myocardium | en |
| dc.subject | spect | en |
| dc.subject | breast cancer | en |
| dc.subject | radiotherapy | en |
| dc.subject | ischemic-heart-disease | en |
| dc.subject | radiation-therapy | en |
| dc.subject | adjuvant radiotherapy | en |
| dc.subject | randomized-trials | en |
| dc.subject | nuclear-medicine | en |
| dc.subject | cardiac toxicity | en |
| dc.subject | morbidity | en |
| dc.subject | damage | en |
| dc.subject | mortality | en |
| dc.subject | risk | en |
| dc.title | Myocardial perfusion imaging with (99) Tc-m-tetrofosmin SPECT in breast cancer patients that received postoperative radiotherapy: a case-control study | en |
| heal.type | journalArticle | - |
| heal.type.en | Journal article | en |
| heal.type.el | Άρθρο Περιοδικού | el |
| heal.identifier.primary | Doi 10.1186/1748-717x-6-151 | - |
| heal.identifier.secondary | <Go to ISI>://000297282900001 | - |
| heal.identifier.secondary | http://www.ro-journal.com/content/pdf/1748-717X-6-151.pdf | - |
| heal.language | en | - |
| heal.access | campus | - |
| heal.recordProvider | Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών και Τεχνολογιών. Τμήμα Βιολογικών Εφαρμογών και Τεχνολογιών | el |
| heal.publicationDate | 2011 | - |
| heal.abstract | Purpose: To evaluate the cardiac toxicity of radiotherapy (RT) in breast cancer (BC) patients employing myocardial perfusion imaging (MPI) with Tc-99 m Tetrofosmin - single photon emission computer tomography (T-SPECT). Materials and methods: We studied 46 BC female patients (28 patients with left and 18 patients with right BC) treated with postoperative RT compared to a control group of 85 age-matched females. The median time of RT to SPECT was 40 months (6-263). Results: Abnormalities in the summed stress score (SSS) were found in 54% of left BC patients, 44.4% of right BC patients, and 32.9% of controls. In left BC patients there were significantly more SSS abnormalities compared to controls (4.0 +/- 3.5 vs 2.6 +/- 2.0, p = 0.05) and possible trend of increased abnormalities of right BC patients (3.7 +/- 3.0 vs 2.6 +/- 2.0, p = 0.14). Multiple regression analysis showed more abnormalities in the MPI of left BC patients compared to controls (SSS, p = 0.0001); Marginal toxicity was also noted in right BC patients (SSS, p = 0.045). No additional toxicity was found in patients that received adjuvant cardiotoxic chemotherapy. All T-SPECT abnormalities were clinically silent. Conclusion: The study suggests that radiation therapy to BC patients result in MPI abnormalities but without apparent clinical consequences. | en |
| heal.journalName | Radiation Oncology | en |
| heal.journalType | peer reviewed | - |
| heal.fullTextAvailability | TRUE | - |
| Appears in Collections: | Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά) | |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| Sioka-2011-Myocardial perfusion.pdf | 235.43 kB | Adobe PDF | View/Open |
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