Please use this identifier to cite or link to this item: https://olympias.lib.uoi.gr/jspui/handle/123456789/17335
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dc.contributor.authorMavridis, A. K.en
dc.contributor.authorMing, L. X.en
dc.contributor.authorHatzipetrou, P.en
dc.contributor.authorLentzaris, G.en
dc.contributor.authorPapanikolaou, N. G.en
dc.contributor.authorTzioufas, A. G.en
dc.contributor.authorMoutsopoulos, H. M.en
dc.date.accessioned2015-11-24T18:38:26Z-
dc.date.available2015-11-24T18:38:26Z-
dc.identifier.issn0961-2033-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/17335-
dc.rightsDefault Licence-
dc.subjectautoantibodiesen
dc.subjectpregnancyen
dc.subjectautoimmunityen
dc.subjectsystemic lupus-erythematosusen
dc.subjectautoimmune rheumatic diseaseen
dc.subjectconnective-tissue diseaseen
dc.subjectantibodiesen
dc.subjectserumen
dc.subjectiggen
dc.subjectimmunoglobulinsen
dc.subjectarthritisen
dc.titlePrevalence of Non-Organ-Specific Autoantibodies in Pregnant and Nonpregnant Healthy Womenen
heal.typejournalArticle-
heal.type.enJournal articleen
heal.type.elΆρθρο Περιοδικούel
heal.identifier.secondary<Go to ISI>://A1992JH33500004-
heal.identifier.secondaryhttp://lup.sagepub.com/content/1/3/141-
heal.languageen-
heal.accesscampus-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών και Τεχνολογιών. Τμήμα Βιολογικών Εφαρμογών και Τεχνολογιώνel
heal.publicationDate1992-
heal.abstractThe prevalence of autoantibodies during pregnancy was studied. Sera from 568 women (203 pregnant and 365 non-pregnant) were tested for autoantibodies to double-stranded DNA, cardiolipin and extractable cellular antigens. Nineteen out of 203 pregnant women (9.4%) had at least one autoantibody against double-stranded DNA or cardiolipin, mainly of the IgM class. The non-pregnant control group had significantly higher incidence of autoantibodies (17.8%; chi-2 = 7.39, P < 0.01). Sixty-six out of 568 women had had spontaneous abortions in their past medical history, but there was no correlation between them and the presence of anticardiolipin antibodies. Two of the non-pregnant women had anti-Ro(SSA) antibodies. These findings suggest that (a) the prevalence of autoantibodies decreases during pregnancy; and (b) the presence of anticardiolipin antibodies in healthy pregnant women does not correlate with any pregnancy-related complications. However, our results indicated that autoimmunity is a rather common disorder in healthy women.en
heal.journalNameLupusen
heal.journalTypepeer reviewed-
heal.fullTextAvailabilityTRUE-
Appears in Collections:Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά)

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