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https://olympias.lib.uoi.gr/jspui/handle/123456789/10842Full metadata record
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Blekas, K. | en |
| dc.contributor.author | Galatsanos, N. P. | en |
| dc.contributor.author | Likas, A. | en |
| dc.contributor.author | Lagaris, I. E. | en |
| dc.date.accessioned | 2015-11-24T17:00:56Z | - |
| dc.date.available | 2015-11-24T17:00:56Z | - |
| dc.identifier.issn | 0278-0062 | - |
| dc.identifier.uri | https://olympias.lib.uoi.gr/jspui/handle/123456789/10842 | - |
| dc.rights | Default Licence | - |
| dc.subject | cross-validated likelihood | en |
| dc.subject | DNA microarray image analysis | en |
| dc.subject | expectation-maximization algorithm | en |
| dc.subject | gaussian mixture models | en |
| dc.subject | markov random fields | en |
| dc.subject | maximum a posteriori | en |
| dc.subject | maximum likelihood | en |
| dc.subject | microarray gridding | en |
| dc.subject | em algorithm | en |
| dc.subject | segmentation | en |
| dc.title | Mixture model analysis of DNA microarray images | en |
| heal.type | journalArticle | - |
| heal.type.en | Journal article | en |
| heal.type.el | Άρθρο Περιοδικού | el |
| heal.identifier.primary | Doi 10.1109/Tmi.2005.848358 | - |
| heal.language | en | - |
| heal.access | campus | - |
| heal.recordProvider | Πανεπιστήμιο Ιωαννίνων. Σχολή Θετικών Επιστημών. Τμήμα Μηχανικών Ηλεκτρονικών Υπολογιστών και Πληροφορικής | el |
| heal.publicationDate | 2005 | - |
| heal.abstract | In this paper, we propose a new methodology for analysis of microarray images. First, a new gridding algorithm is proposed for determining the individual spots and their borders. Then, a Gaussian mixture model (GMM) approach is presented for the analysis of the individual spot images. The main advantages of the proposed methodology are modeling flexibility and adaptability to the data, which are well-known strengths of GMM. The maximum likelihood and maximum a posteriori approaches are used to estimate the GMM parameters via the expectation maximization algorithm. The proposed approach has the ability to detect and compensate for artifacts that might occur in microarray images. This is accomplished by a model-based criterion that selects the number of the mixture components. We present numerical experiments with artificial and real data where we compare the proposed approach with previous ones and existing software tools for microarray image analysis and demonstrate its advantages. | en |
| heal.journalName | IEEE Trans Med Imaging | en |
| heal.journalType | peer reviewed | - |
| heal.fullTextAvailability | TRUE | - |
| Appears in Collections: | Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά) | |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| Lagaris-2005-Mixture model analysis of DNA microarray images.pdf | 756.34 kB | Adobe PDF | View/Open Request a copy |
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