Please use this identifier to cite or link to this item:
https://olympias.lib.uoi.gr/jspui/handle/123456789/10134Full metadata record
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | V.Tsikaris | en |
| dc.contributor.author | M.Sakarellos-Daitsiotis | en |
| dc.contributor.author | E.Panou-Pomonis | en |
| dc.contributor.author | E.Detsikas | en |
| dc.contributor.author | C. Sakarellos | en |
| dc.contributor.author | M.T. Cung | en |
| dc.contributor.author | M. Marraud | en |
| dc.date.accessioned | 2015-11-24T16:54:14Z | - |
| dc.date.available | 2015-11-24T16:54:14Z | - |
| dc.identifier.uri | https://olympias.lib.uoi.gr/jspui/handle/123456789/10134 | - |
| dc.rights | Default Licence | - |
| dc.title | 1H-NMR studies on arginine tripeptides: evidence for guanidinium-C-terminal carboxylate interactions | en |
| heal.type | journalArticle | - |
| heal.type.en | Journal article | en |
| heal.type.el | Άρθρο Περιοδικού | el |
| heal.identifier.secondary | http://www.ncbi.nlm.nih.gov/pubmed/1581638 | - |
| heal.language | en | - |
| heal.access | campus | - |
| heal.recordProvider | Πανεπιστήμιο Ιωαννίνων. Σχολή Θετικών Επιστημών. Τμήμα Χημείας | el |
| heal.publicationDate | 1992 | - |
| heal.abstract | Guanidinium-C-terminal carboxylate interactions are involved in the establishment of the secondary structure of various biologically active peptide sequences. The conformational properties of a series of arginine-containing tripeptides, L-Arg-X-Gly (X = L-Ala, Val, Leu), in DMSO solutions at physiological pH, have been studied by means of 1D and 2D 1H-NMR spectroscopy. Measurements of the chemical shifts, NOE effects and temperature coefficients showed that the ArgN epsilon H and ArgN eta H2 groups form two hydrogen bonds with the C-terminal carboxylate moiety, whereas the ArgN alpha-terminal nitrogen is in the amino state. Our results point out the significant contribution of the C-terminal carboxylate group, at physiological pH, in the stabilization of the Arg side-chain structure in peptides simultaneously containing arginine residues and carboxy terminal sequences. | en |
| heal.journalName | Peptide Research | en |
| heal.journalType | peer reviewed | - |
| heal.fullTextAvailability | TRUE | - |
| Appears in Collections: | Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά). ΧΗΜ | |
Files in This Item:
There are no files associated with this item.
This item is licensed under a Creative Commons License
