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dc.contributor.authorTheodorou-Kassioumis, V.en
dc.contributor.authorBiris, N.en
dc.contributor.authorSakarellos, C.en
dc.contributor.authorTsikaris, V.en
dc.date.accessioned2015-11-24T16:53:38Z-
dc.date.available2015-11-24T16:53:38Z-
dc.identifier.issn0040-4039-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/10046-
dc.rightsDefault Licence-
dc.subjectisotopic enrichmenten
dc.subjectoxygen-17en
dc.subjecto-17 nmren
dc.subjectaspartic aciden
dc.subjectrgd peptidesen
dc.subjectsolid-phase o-17 peptide enrichmenten
dc.subjecto-17-nmren
dc.titleA convenient and rapid method for the selective oxygen-17 enrichment of aspartyl peptides during solid-phase synthesisen
heal.typejournalArticle-
heal.type.enJournal articleen
heal.type.elΆρθρο Περιοδικούel
heal.identifier.primaryDoi 10.1016/S0040-4039(01)01632-X-
heal.identifier.secondary<Go to ISI>://000171556600042-
heal.identifier.secondaryhttp://ac.els-cdn.com/S004040390101632X/1-s2.0-S004040390101632X-main.pdf?_tid=74b29c30-3574-11e3-90ed-00000aab0f02&acdnat=1381826184_2f2f4259b5592d92ea527a7e8f4bea5f-
heal.languageen-
heal.accesscampus-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Θετικών Επιστημών. Τμήμα Χημείαςel
heal.publicationDate2001-
heal.abstractIn this work we describe, for the first time, a rapid and efficient method for O-17 selective labeling on the beta -carboxyl group of an aspartic acid residue already incorporated into a peptide sequence anchored on a solid-phase support. The beta -O-benzyl ester of the Asp residue of the Ac-RGD-benzydrylamine resin was successfully saponified using (NaOH)-O-17 in a methanol/ dichloromethane mixture. The O-17 selective enriched peptide was then released from the solid support by acidic cleavage. The O-17 NMR spectrum confirmed the O-17 labeling of the Asp beta -carboxylate. (C) 2001 Elsevier Science Ltd. All rights reserved.en
heal.publisherElsevieren
heal.journalNameTetrahedron Letten
heal.journalTypepeer reviewed-
heal.fullTextAvailabilityTRUE-
Appears in Collections:Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά). ΧΗΜ

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